American Airlines flights from Knoxville to Columbus

Recent searches for flights from Knoxville to Columbus

Aug 2026
From$288*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$274*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$299*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $288
cmp-daily-histogram-bars-legend-max-price-aria-label $662
Displaying fares for August-2026
  • TYS–CMH, 08/04/26 – 08/11/26: From $662
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    AUG

  • TYS–CMH, 08/05/26 – 08/12/26: From $662
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  • TYS–CMH, 08/06/26 – 08/13/26: From $662
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  • TYS–CMH, 08/07/26 – 08/14/26: From $662
    07

    Fr

  • TYS–CMH, 08/08/26 – 08/15/26: From $662
    08

    Sa

  • TYS–CMH, 08/09/26 – 08/16/26: From $662
    09

    Su

  • TYS–CMH, 08/10/26 – 08/17/26: From $662
    10

    Mo

  • TYS–CMH, 08/11/26 – 08/18/26: From $577
    11

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  • TYS–CMH, 08/12/26 – 08/19/26: From $577
    12

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  • TYS–CMH, 08/13/26 – 08/20/26: From $577
    13

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  • TYS–CMH, 08/14/26 – 08/21/26: From $577
    14

    Fr

  • TYS–CMH, 08/15/26 – 08/22/26: From $577
    15

    Sa

  • TYS–CMH, 08/16/26 – 08/23/26: From $577
    16

    Su

  • TYS–CMH, 08/17/26 – 08/18/26: From $447
    17

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  • TYS–CMH, 08/18/26 – 08/25/26: From $375
    18

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  • TYS–CMH, 08/19/26 – 08/26/26: From $375
    19

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  • TYS–CMH, 08/20/26 – 08/27/26: From $375
    20

    Th

  • TYS–CMH, 08/21/26 – 08/28/26: From $386
    21

    Fr

  • TYS–CMH, 08/22/26 – 08/29/26: From $375
    22

    Sa

  • TYS–CMH, 08/23/26 – 08/30/26: From $417
    23

    Su

  • TYS–CMH, 08/24/26 – 08/31/26: From $375
    24

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  • TYS–CMH, 08/25/26 – 09/01/26: From $303
    25

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  • TYS–CMH, 08/26/26 – 09/02/26: From $303
    26

    We

  • TYS–CMH, 08/27/26 – 09/03/26: From $303
    27

    Th

  • TYS–CMH, 08/28/26 – 09/04/26: From $382
    28

    Fr

  • TYS–CMH, 08/29/26 – 09/05/26: From $288
    29

    Sa

  • TYS–CMH, 08/30/26 – 09/06/26: From $330
    30

    Su

  • TYS–CMH, 08/31/26 – 09/07/26: From $303
    31

    Mo

  • TYS–CMH: cmp-view-offers-disclaimer. Find Offers
    01

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    SEP

  • TYS–CMH: cmp-view-offers-disclaimer. Find Offers
    02

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  • TYS–CMH, 09/03/26 – 09/10/26: From $289
    03

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    • range$288-$662

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Columbus flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Columbus (CMH)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $274Fare subject to changes
    Updated: 8 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    09/09/26 - 09/10/26

    Round trip

    Economy

    from
    $275Fare subject to changes
    Updated: 18 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $288Fare subject to changes
    Updated: 8 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $289Fare subject to changes
    Updated: 18 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $289Fare subject to changes
    Updated: 8 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    09/10/26 - 09/17/26

    Round trip

    Economy

    from
    $289Fare subject to changes
    Updated: 8 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $289Fare subject to changes
    Updated: 8 hours ago

    Knoxville (TYS)to

    Columbus (CMH)
    10/30/26 - 11/06/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Columbus

    Looking for lower fares on your trip from Knoxville to Columbus? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Knoxville to Columbus