American Airlines flights from Louisville to Panama City

Recent searches for flights from Louisville to Panama City

Sep 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
Nov 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $309
cmp-daily-histogram-bars-legend-max-price-aria-label $931
Displaying fares for September-2026
  • SDF–ECP, 09/04/26 – 09/11/26: From $735
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    Fr

    SEP

  • SDF–ECP, 09/05/26 – 09/12/26: From $735
    05

    Sa

  • SDF–ECP, 09/06/26 – 09/13/26: From $735
    06

    Su

  • SDF–ECP, 09/07/26 – 09/14/26: From $735
    07

    Mo

  • SDF–ECP, 09/08/26 – 09/15/26: From $735
    08

    Tu

  • SDF–ECP, 09/09/26 – 09/16/26: From $735
    09

    We

  • SDF–ECP, 09/10/26 – 09/17/26: From $605
    10

    Th

  • SDF–ECP, 09/11/26 – 09/18/26: From $616
    11

    Fr

  • SDF–ECP, 09/12/26 – 09/19/26: From $605
    12

    Sa

  • SDF–ECP, 09/13/26 – 09/20/26: From $676
    13

    Su

  • SDF–ECP, 09/14/26 – 09/21/26: From $751
    14

    Mo

  • SDF–ECP, 09/15/26 – 09/22/26: From $605
    15

    Tu

  • SDF–ECP, 09/16/26 – 09/23/26: From $605
    16

    We

  • SDF–ECP, 09/17/26 – 09/24/26: From $702
    17

    Th

  • SDF–ECP, 09/18/26 – 09/25/26: From $568
    18

    Fr

  • SDF–ECP, 09/19/26 – 09/26/26: From $477
    19

    Sa

  • SDF–ECP, 09/20/26 – 09/27/26: From $568
    20

    Su

  • SDF–ECP, 09/21/26 – 09/28/26: From $568
    21

    Mo

  • SDF–ECP, 09/22/26 – 09/29/26: From $393
    22

    Tu

  • SDF–ECP, 09/23/26 – 09/30/26: From $393
    23

    We

  • SDF–ECP, 09/24/26 – 10/01/26: From $654
    24

    Th

  • SDF–ECP, 09/25/26 – 10/02/26: From $620
    25

    Fr

  • SDF–ECP, 09/26/26 – 10/03/26: From $525
    26

    Sa

  • SDF–ECP, 09/27/26 – 10/04/26: From $568
    27

    Su

  • SDF–ECP, 09/28/26 – 10/05/26: From $931
    28

    Mo

  • SDF–ECP, 09/29/26 – 10/06/26: From $309
    29

    Tu

  • SDF–ECP, 09/30/26 – 10/07/26: From $393
    30

    We

  • SDF–ECP: cmp-view-offers-disclaimer. Find Offers
    01

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    OCT

  • SDF–ECP: cmp-view-offers-disclaimer. Find Offers
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  • SDF–ECP: cmp-view-offers-disclaimer. Find Offers
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    • range$309-$931

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Louisville to Panama City flights

    $
    keyboard_arrow_down

    Louisville (SDF)to

    Panama City (ECP)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Louisville (SDF)to

    Panama City (ECP)
    11/12/26 - 11/19/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Louisville to Panama City

    Looking for lower fares on your trip from Louisville to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Louisville to Panama City