American Airlines flights from Mcallen to San Francisco

Recent searches for flights from Mcallen to San Francisco

Aug 2026
From$553*
Updated: 3 hours ago
Round tripIEconomy
Sep 2026
From$247*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$247*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $247
cmp-daily-histogram-bars-legend-max-price-aria-label $893
Displaying fares for August-2026
  • MFE–SFO, 08/31/26 – 09/07/26: From $553
    31

    Mo

    AUG

  • MFE–SFO, 09/01/26 – 09/08/26: From $407
    01

    Tu

  • MFE–SFO, 09/02/26 – 09/09/26: From $367
    02

    We

  • MFE–SFO, 09/03/26 – 09/22/26: From $333
    03

    Th

  • MFE–SFO, 09/04/26 – 09/11/26: From $440
    04

    Fr

  • MFE–SFO, 09/05/26 – 09/12/26: From $367
    05

    Sa

  • MFE–SFO, 09/06/26 – 09/13/26: From $289
    06

    Su

  • MFE–SFO, 09/07/26 – 09/14/26: From $893
    07

    Mo

  • MFE–SFO, 09/08/26 – 09/15/26: From $719
    08

    Tu

  • MFE–SFO, 09/09/26 – 09/13/26: From $289
    09

    We

  • MFE–SFO, 09/10/26 – 09/13/26: From $289
    10

    Th

  • MFE–SFO, 09/11/26 – 09/18/26: From $438
    11

    Fr

  • MFE–SFO, 09/12/26 – 09/19/26: From $289
    12

    Sa

  • MFE–SFO, 09/13/26 – 09/20/26: From $438
    13

    Su

  • MFE–SFO, 09/14/26 – 09/21/26: From $872
    14

    Mo

  • MFE–SFO, 09/15/26 – 09/22/26: From $257
    15

    Tu

  • MFE–SFO, 09/16/26 – 09/23/26: From $257
    16

    We

  • MFE–SFO, 09/17/26 – 09/24/26: From $257
    17

    Th

  • MFE–SFO, 09/18/26 – 09/25/26: From $338
    18

    Fr

  • MFE–SFO, 09/19/26 – 09/26/26: From $257
    19

    Sa

  • MFE–SFO, 09/20/26 – 09/27/26: From $338
    20

    Su

  • MFE–SFO, 09/21/26 – 09/28/26: From $429
    21

    Mo

  • MFE–SFO, 09/22/26 – 09/29/26: From $287
    22

    Tu

  • MFE–SFO, 09/23/26 – 09/30/26: From $287
    23

    We

  • MFE–SFO, 09/24/26 – 10/01/26: From $287
    24

    Th

  • MFE–SFO, 09/25/26 – 10/02/26: From $378
    25

    Fr

  • MFE–SFO, 09/26/26 – 10/03/26: From $247
    26

    Sa

  • MFE–SFO: cmp-view-offers-disclaimer. Find Offers
    27

    Su

  • MFE–SFO: cmp-view-offers-disclaimer. Find Offers
    28

    Mo

  • MFE–SFO: cmp-view-offers-disclaimer. Find Offers
    29

    Tu

  • MFE–SFO, 09/30/26 – 10/07/26: From $247
    30

    We

    • range$247-$893

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Mcallen to San Francisco flights

    $
    keyboard_arrow_down

    Mcallen (MFE)to

    San Francisco (SFO)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    11/02/26 - 11/09/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    Mcallen (MFE)to

    San Francisco (SFO)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $247Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Mcallen to San Francisco

    Looking for lower fares on your trip from Mcallen to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Mcallen to San Francisco