Flights from Panama City with American Airlines

Popular flights from Panama City

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  • Panama City (ECP)to

    New York (LGA)
    06/17/25 - 06/24/25
    from
    $299Fare subject to changes
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Austin (AUS)
    06/07/25 - 06/14/25
    from
    $217Fare subject to changes
    Updated: 3 hours ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Denver (DEN)
    06/17/25 - 06/24/25
    from
    $367Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Honolulu (HNL)
    06/10/25 - 06/17/25
    from
    $1,063Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

  • Panama City (ECP)to

    Boston (BOS)
    06/07/25 - 06/14/25
    from
    $355Fare subject to changes
    Updated: 3 hours ago
    Round trip
    I
    Economy

    Panama City (ECP)to

    Los Angeles (LAX)
    06/11/25 - 06/18/25
    from
    $343Fare subject to changes
    Updated: 2 hours ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Find deals on flights from Panama City

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Panama City (ECP)to

Dallas (DFW)
07/01/25 - 07/08/25

Round trip

I

Economy

from
$271Fare subject to changes
Updated: 7 hours ago

Panama City (ECP)to

Charlotte (CLT)
06/25/25 - 07/02/25

Round trip

I

Economy

from
$313Fare subject to changes
Updated: 6 hours ago

Panama City (ECP)to

Washington, D.C. (DCA)
08/05/25 - 08/12/25

Round trip

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Economy

from
$303Fare subject to changes
Updated: 13 hours ago

Panama City (ECP)to

Philadelphia (PHL)
06/24/25 - 07/01/25

Round trip

I

Economy

from
$334Fare subject to changes
Updated: 55 minutes ago

Panama City (ECP)to

New York (LGA)
06/24/25 - 07/01/25

Round trip

I

Economy

from
$249Fare subject to changes
Updated: 2 hours ago

Panama City (ECP)to

Austin (AUS)
06/24/25 - 07/01/25

Round trip

I

Economy

from
$217Fare subject to changes
Updated: 3 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Destinations from Panama City

Explore American Airlines's Top-Pick Destinations