American Airlines flights from Panama City to San Diego

Recent searches for flights from Panama City to San Diego

Aug 2026
From$379*
Updated: 12 hours ago
Round tripIEconomy
Sep 2026
From$263*
Updated: 12 hours ago
Round tripIEconomy
Oct 2026
From$263*
Updated: 12 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $323
cmp-daily-histogram-bars-legend-max-price-aria-label $741
Displaying fares for August-2026
  • ECP–SAN, 08/12/26 – 08/19/26: From $581
    12

    We

    AUG

  • ECP–SAN, 08/13/26 – 08/20/26: From $741
    13

    Th

  • ECP–SAN, 08/14/26 – 08/21/26: From $741
    14

    Fr

  • ECP–SAN, 08/15/26 – 08/22/26: From $581
    15

    Sa

  • ECP–SAN, 08/16/26 – 08/23/26: From $741
    16

    Su

  • ECP–SAN, 08/17/26 – 08/24/26: From $741
    17

    Mo

  • ECP–SAN, 08/18/26 – 08/25/26: From $514
    18

    Tu

  • ECP–SAN, 08/19/26 – 08/26/26: From $514
    19

    We

  • ECP–SAN, 08/20/26 – 08/27/26: From $604
    20

    Th

  • ECP–SAN, 08/21/26 – 08/28/26: From $604
    21

    Fr

  • ECP–SAN, 08/22/26 – 08/29/26: From $514
    22

    Sa

  • ECP–SAN, 08/23/26 – 08/30/26: From $604
    23

    Su

  • ECP–SAN, 08/24/26 – 08/31/26: From $556
    24

    Mo

  • ECP–SAN, 08/25/26 – 09/01/26: From $380
    25

    Tu

  • ECP–SAN, 08/26/26 – 09/02/26: From $380
    26

    We

  • ECP–SAN, 08/27/26 – 09/03/26: From $609
    27

    Th

  • ECP–SAN, 08/28/26 – 09/04/26: From $443
    28

    Fr

  • ECP–SAN, 08/29/26 – 09/05/26: From $379
    29

    Sa

  • ECP–SAN, 08/30/26 – 09/06/26: From $449
    30

    Su

  • ECP–SAN, 08/31/26 – 09/07/26: From $557
    31

    Mo

  • ECP–SAN, 09/01/26 – 09/08/26: From $420
    01

    Tu

    SEP

  • ECP–SAN, 09/02/26 – 09/09/26: From $420
    02

    We

  • ECP–SAN, 09/03/26 – 09/10/26: From $417
    03

    Th

  • ECP–SAN, 09/04/26 – 09/11/26: From $323
    04

    Fr

  • ECP–SAN, 09/05/26 – 09/12/26: From $341
    05

    Sa

  • ECP–SAN, 09/06/26 – 09/13/26: From $449
    06

    Su

  • ECP–SAN, 09/07/26 – 09/14/26: From $735
    07

    Mo

  • ECP–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Tu

  • ECP–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    We

  • ECP–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Th

  • ECP–SAN, 09/11/26 – 09/18/26: From $477
    11

    Fr

    • range$323-$741

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Panama City to San Diego flights

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    Panama City (ECP)to

    San Diego (SAN)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    09/28/26 - 10/05/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 12 hours ago

    Panama City (ECP)to

    San Diego (SAN)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 12 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Panama City to San Diego

    Looking for lower fares on your trip from Panama City to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Panama City to San Diego