American Airlines flights from Saint Louis to San Diego

Recent searches for flights from Saint Louis to San Diego

Sep 2026
From$292*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$237*
Updated: 4 hours ago
Round tripIEconomy
Nov 2026
From$237*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $237
cmp-daily-histogram-bars-legend-max-price-aria-label $689
Displaying fares for September-2026
  • STL–SAN, 09/15/26 – 09/22/26: From $411
    15

    Tu

    SEP

  • STL–SAN, 09/16/26 – 09/23/26: From $411
    16

    We

  • STL–SAN, 09/17/26 – 09/24/26: From $648
    17

    Th

  • STL–SAN, 09/18/26 – 09/25/26: From $489
    18

    Fr

  • STL–SAN, 09/19/26 – 09/26/26: From $411
    19

    Sa

  • STL–SAN, 09/20/26 – 09/27/26: From $489
    20

    Su

  • STL–SAN, 09/21/26 – 09/28/26: From $489
    21

    Mo

  • STL–SAN, 09/22/26 – 09/29/26: From $411
    22

    Tu

  • STL–SAN, 09/23/26 – 09/30/26: From $411
    23

    We

  • STL–SAN, 09/24/26 – 10/01/26: From $418
    24

    Th

  • STL–SAN, 09/25/26 – 10/02/26: From $418
    25

    Fr

  • STL–SAN, 09/26/26 – 10/03/26: From $411
    26

    Sa

  • STL–SAN, 09/27/26 – 10/04/26: From $484
    27

    Su

  • STL–SAN, 09/28/26 – 10/05/26: From $417
    28

    Mo

  • STL–SAN, 09/29/26 – 10/06/26: From $292
    29

    Tu

  • STL–SAN, 09/30/26 – 10/07/26: From $292
    30

    We

  • STL–SAN, 10/01/26 – 10/08/26: From $446
    01

    Th

    OCT

  • STL–SAN, 10/02/26 – 10/06/26: From $335
    02

    Fr

  • STL–SAN, 10/03/26 – 10/10/26: From $302
    03

    Sa

  • STL–SAN, 10/04/26 – 10/11/26: From $513
    04

    Su

  • STL–SAN, 10/05/26 – 10/12/26: From $383
    05

    Mo

  • STL–SAN, 10/06/26 – 10/13/26: From $237
    06

    Tu

  • STL–SAN, 10/07/26 – 10/14/26: From $343
    07

    We

  • STL–SAN, 10/08/26 – 10/15/26: From $368
    08

    Th

  • STL–SAN, 10/09/26 – 10/16/26: From $383
    09

    Fr

  • STL–SAN, 10/10/26 – 10/17/26: From $257
    10

    Sa

  • STL–SAN, 10/11/26 – 10/18/26: From $689
    11

    Su

  • STL–SAN, 10/12/26 – 10/19/26: From $412
    12

    Mo

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    14

    We

    • range$237-$689

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to San Diego flights

    $
    keyboard_arrow_down

    Saint Louis (STL)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    San Diego (SAN)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $237Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to San Diego

    Looking for lower fares on your trip from Saint Louis to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Saint Louis to San Diego