American Airlines flights from Minneapolis to San Diego

Recent searches for flights from Minneapolis to San Diego

Aug 2026
From$391*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$391*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$396*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $391
cmp-daily-histogram-bars-legend-max-price-aria-label $804
Displaying fares for August-2026
  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    04

    Tu

    AUG

  • MSP–SAN, 08/05/26 – 08/12/26: From $804
    05

    We

  • MSP–SAN, 08/06/26 – 08/13/26: From $804
    06

    Th

  • MSP–SAN, 08/07/26 – 08/14/26: From $804
    07

    Fr

  • MSP–SAN, 08/08/26 – 08/15/26: From $804
    08

    Sa

  • MSP–SAN, 08/09/26 – 08/16/26: From $804
    09

    Su

  • MSP–SAN, 08/10/26 – 08/17/26: From $804
    10

    Mo

  • MSP–SAN, 08/11/26 – 08/18/26: From $629
    11

    Tu

  • MSP–SAN, 08/12/26 – 08/19/26: From $629
    12

    We

  • MSP–SAN, 08/13/26 – 08/20/26: From $629
    13

    Th

  • MSP–SAN, 08/14/26 – 08/21/26: From $629
    14

    Fr

  • MSP–SAN, 08/15/26 – 08/22/26: From $629
    15

    Sa

  • MSP–SAN, 08/16/26 – 08/23/26: From $629
    16

    Su

  • MSP–SAN, 08/17/26 – 08/24/26: From $629
    17

    Mo

  • MSP–SAN, 08/18/26 – 08/25/26: From $474
    18

    Tu

  • MSP–SAN, 08/19/26 – 08/26/26: From $474
    19

    We

  • MSP–SAN, 08/20/26 – 08/27/26: From $474
    20

    Th

  • MSP–SAN, 08/21/26 – 08/28/26: From $499
    21

    Fr

  • MSP–SAN, 08/22/26 – 08/29/26: From $474
    22

    Sa

  • MSP–SAN, 08/23/26 – 08/30/26: From $499
    23

    Su

  • MSP–SAN, 08/24/26 – 08/31/26: From $474
    24

    Mo

  • MSP–SAN, 08/25/26 – 09/01/26: From $419
    25

    Tu

  • MSP–SAN, 08/26/26 – 09/02/26: From $419
    26

    We

  • MSP–SAN, 08/27/26 – 09/03/26: From $478
    27

    Th

  • MSP–SAN, 08/28/26 – 09/04/26: From $449
    28

    Fr

  • MSP–SAN, 08/29/26 – 09/05/26: From $391
    29

    Sa

  • MSP–SAN, 08/30/26 – 09/06/26: From $449
    30

    Su

  • MSP–SAN, 08/31/26 – 09/07/26: From $461
    31

    Mo

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    01

    Tu

    SEP

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    02

    We

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    03

    Th

    • range$391-$804

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Minneapolis to San Diego flights

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    keyboard_arrow_down

    Minneapolis (MSP)to

    San Diego (SAN)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    09/11/26 - 09/18/26

    Round trip

    Economy

    from
    $396Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $396Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    09/06/26 - 09/13/26

    Round trip

    Economy

    from
    $396Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    10/30/26 - 11/06/26

    Round trip

    Economy

    from
    $396Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    09/04/26 - 09/11/26

    Round trip

    Economy

    from
    $396Fare subject to changes
    Updated: 1 hour ago

    Minneapolis (MSP)to

    San Diego (SAN)
    10/15/26 - 10/22/26

    Round trip

    Economy

    from
    $419Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Minneapolis to San Diego

    Looking for lower fares on your trip from Minneapolis to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Minneapolis to San Diego