American Airlines flights from Portland, OR to San Diego

Recent searches for flights from Portland, OR to San Diego

Sep 2026
From$257*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$217*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$217*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $257
cmp-daily-histogram-bars-legend-max-price-aria-label $555
Displaying fares for September-2026
  • PDX–SAN, 09/06/26 – 09/13/26: From $351
    06

    Su

    SEP

  • PDX–SAN, 09/07/26 – 09/14/26: From $455
    07

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  • PDX–SAN, 09/08/26 – 09/15/26: From $555
    08

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  • PDX–SAN, 09/09/26 – 09/16/26: From $351
    09

    We

  • PDX–SAN, 09/10/26 – 09/17/26: From $351
    10

    Th

  • PDX–SAN, 09/11/26 – 09/18/26: From $351
    11

    Fr

  • PDX–SAN, 09/12/26 – 09/19/26: From $351
    12

    Sa

  • PDX–SAN, 09/13/26 – 09/20/26: From $420
    13

    Su

  • PDX–SAN, 09/14/26 – 09/21/26: From $555
    14

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  • PDX–SAN, 09/15/26 – 09/22/26: From $351
    15

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  • PDX–SAN, 09/16/26 – 09/23/26: From $351
    16

    We

  • PDX–SAN, 09/17/26 – 09/24/26: From $351
    17

    Th

  • PDX–SAN, 09/18/26 – 09/25/26: From $420
    18

    Fr

  • PDX–SAN, 09/19/26 – 09/26/26: From $334
    19

    Sa

  • PDX–SAN, 09/20/26 – 09/27/26: From $384
    20

    Su

  • PDX–SAN, 09/21/26 – 09/28/26: From $352
    21

    Mo

  • PDX–SAN, 09/22/26 – 09/29/26: From $334
    22

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  • PDX–SAN, 09/23/26 – 09/30/26: From $398
    23

    We

  • PDX–SAN, 09/24/26 – 10/01/26: From $334
    24

    Th

  • PDX–SAN, 09/25/26 – 10/02/26: From $398
    25

    Fr

  • PDX–SAN, 09/26/26 – 10/03/26: From $297
    26

    Sa

  • PDX–SAN, 09/27/26 – 10/04/26: From $548
    27

    Su

  • PDX–SAN, 09/28/26 – 10/05/26: From $312
    28

    Mo

  • PDX–SAN, 09/29/26 – 10/06/26: From $257
    29

    Tu

  • PDX–SAN, 09/30/26 – 10/07/26: From $257
    30

    We

  • PDX–SAN, 10/01/26 – 10/08/26: From $357
    01

    Th

    OCT

  • PDX–SAN, 10/02/26 – 10/09/26: From $508
    02

    Fr

  • PDX–SAN: cmp-view-offers-disclaimer. Find Offers
    03

    Sa

  • PDX–SAN: cmp-view-offers-disclaimer. Find Offers
    04

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  • PDX–SAN: cmp-view-offers-disclaimer. Find Offers
    05

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    • range$257-$555

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, OR to San Diego flights

    $
    keyboard_arrow_down

    Portland, OR (PDX)to

    San Diego (SAN)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    San Diego (SAN)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $217Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, OR to San Diego

    Looking for lower fares on your trip from Portland, OR to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
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    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Portland, OR to San Diego