American Airlines flights from Orlando to San Diego

Recent searches for flights from Orlando to San Diego

Sep 2026
From$257*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$257*
Updated: 1 hour ago
Round tripIEconomy
Nov 2026
From$257*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $257
cmp-daily-histogram-bars-legend-max-price-aria-label $602
Displaying fares for September-2026
  • MCO–SAN: cmp-view-offers-disclaimer. Find Offers
    01

    Tu

    SEP

  • MCO–SAN, 09/02/26 – 09/09/26: From $451
    02

    We

  • MCO–SAN, 09/03/26 – 09/10/26: From $451
    03

    Th

  • MCO–SAN, 09/04/26 – 09/11/26: From $451
    04

    Fr

  • MCO–SAN, 09/05/26 – 09/12/26: From $451
    05

    Sa

  • MCO–SAN, 09/06/26 – 09/13/26: From $451
    06

    Su

  • MCO–SAN, 09/07/26 – 09/14/26: From $451
    07

    Mo

  • MCO–SAN, 09/08/26 – 09/15/26: From $451
    08

    Tu

  • MCO–SAN, 09/09/26 – 09/16/26: From $451
    09

    We

  • MCO–SAN, 09/10/26 – 09/12/26: From $451
    10

    Th

  • MCO–SAN, 09/11/26 – 09/18/26: From $544
    11

    Fr

  • MCO–SAN, 09/12/26 – 09/16/26: From $451
    12

    Sa

  • MCO–SAN, 09/13/26 – 09/20/26: From $602
    13

    Su

  • MCO–SAN, 09/14/26 – 09/21/26: From $451
    14

    Mo

  • MCO–SAN, 09/15/26 – 09/22/26: From $392
    15

    Tu

  • MCO–SAN, 09/16/26 – 09/23/26: From $392
    16

    We

  • MCO–SAN, 09/17/26 – 09/24/26: From $531
    17

    Th

  • MCO–SAN, 09/18/26 – 09/25/26: From $451
    18

    Fr

  • MCO–SAN, 09/19/26 – 09/26/26: From $481
    19

    Sa

  • MCO–SAN, 09/20/26 – 09/27/26: From $453
    20

    Su

  • MCO–SAN, 09/21/26 – 09/28/26: From $412
    21

    Mo

  • MCO–SAN, 09/22/26 – 09/29/26: From $257
    22

    Tu

  • MCO–SAN, 09/23/26 – 09/30/26: From $352
    23

    We

  • MCO–SAN, 09/24/26 – 10/01/26: From $366
    24

    Th

  • MCO–SAN, 09/25/26 – 10/02/26: From $380
    25

    Fr

  • MCO–SAN, 09/26/26 – 10/03/26: From $318
    26

    Sa

  • MCO–SAN, 09/27/26 – 10/04/26: From $567
    27

    Su

  • MCO–SAN, 09/28/26 – 10/05/26: From $338
    28

    Mo

  • MCO–SAN: cmp-view-offers-disclaimer. Find Offers
    29

    Tu

  • MCO–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    We

    • range$257-$602

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Orlando to San Diego flights

    $
    keyboard_arrow_down

    Orlando (MCO)to

    San Diego (SAN)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Orlando (MCO)to

    San Diego (SAN)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Orlando to San Diego

    Looking for lower fares on your trip from Orlando to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Orlando to San Diego