American Airlines flights from Greenville to San Diego

Recent searches for flights from Greenville to San Diego

Aug 2026
From$350*
Updated: 7 hours ago
Round tripIEconomy
Sep 2026
From$368*
Updated: 15 hours ago
Round tripIEconomy
Oct 2026
From$369*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $350
cmp-daily-histogram-bars-legend-max-price-aria-label $741
Displaying fares for August-2026
  • GSP–SAN, 08/05/26 – 08/12/26: From $581
    05

    We

    AUG

  • GSP–SAN, 08/06/26 – 08/13/26: From $741
    06

    Th

  • GSP–SAN, 08/07/26 – 08/14/26: From $741
    07

    Fr

  • GSP–SAN, 08/08/26 – 08/15/26: From $581
    08

    Sa

  • GSP–SAN, 08/09/26 – 08/16/26: From $741
    09

    Su

  • GSP–SAN, 08/10/26 – 08/17/26: From $741
    10

    Mo

  • GSP–SAN, 08/11/26 – 08/18/26: From $512
    11

    Tu

  • GSP–SAN, 08/12/26 – 08/19/26: From $512
    12

    We

  • GSP–SAN, 08/13/26 – 08/20/26: From $669
    13

    Th

  • GSP–SAN, 08/14/26 – 08/21/26: From $669
    14

    Fr

  • GSP–SAN, 08/15/26 – 08/22/26: From $512
    15

    Sa

  • GSP–SAN, 08/16/26 – 08/28/26: From $582
    16

    Su

  • GSP–SAN, 08/17/26 – 08/28/26: From $582
    17

    Mo

  • GSP–SAN, 08/18/26 – 08/25/26: From $367
    18

    Tu

  • GSP–SAN, 08/19/26 – 08/26/26: From $367
    19

    We

  • GSP–SAN, 08/20/26 – 08/27/26: From $474
    20

    Th

  • GSP–SAN, 08/21/26 – 08/27/26: From $474
    21

    Fr

  • GSP–SAN, 08/22/26 – 08/29/26: From $367
    22

    Sa

  • GSP–SAN, 08/23/26 – 08/30/26: From $564
    23

    Su

  • GSP–SAN, 08/24/26 – 08/31/26: From $474
    24

    Mo

  • GSP–SAN, 08/25/26 – 09/05/26: From $350
    25

    Tu

  • GSP–SAN, 08/26/26 – 09/02/26: From $367
    26

    We

  • GSP–SAN, 08/27/26 – 09/03/26: From $444
    27

    Th

  • GSP–SAN, 08/28/26 – 09/04/26: From $423
    28

    Fr

  • GSP–SAN, 08/29/26 – 09/05/26: From $350
    29

    Sa

  • GSP–SAN, 08/30/26 – 09/06/26: From $463
    30

    Su

  • GSP–SAN, 08/31/26 – 09/07/26: From $520
    31

    Mo

  • GSP–SAN, 09/01/26 – 09/08/26: From $368
    01

    Tu

    SEP

  • GSP–SAN: cmp-view-offers-disclaimer. Find Offers
    02

    We

  • GSP–SAN: cmp-view-offers-disclaimer. Find Offers
    03

    Th

  • GSP–SAN, 09/04/26 – 09/11/26: From $378
    04

    Fr

    • range$350-$741

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Greenville to San Diego flights

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    Greenville (GSP)to

    San Diego (SAN)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $350Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/25/26 - 09/05/26

    Round trip

    Economy

    from
    $350Fare subject to changes
    Updated: 3 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/18/26 - 08/25/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/19/26 - 08/26/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/22/26 - 08/29/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/25/26 - 09/01/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    08/26/26 - 09/02/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 7 hours ago

    Greenville (GSP)to

    San Diego (SAN)
    09/01/26 - 09/08/26

    Round trip

    Economy

    from
    $368Fare subject to changes
    Updated: 15 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Greenville to San Diego

    Looking for lower fares on your trip from Greenville to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Greenville to San Diego