American Airlines flights to Grand Cayman from $280*

Popular flights to Grand Cayman on American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Grand Cayman

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Charlotte (CLT)to

Grand Cayman (GCM)
11/18/25 - 11/25/25

Round trip

Economy

from
$330Fare subject to changes
Updated: 26 minutes ago

Miami (MIA)to

Grand Cayman (GCM)
12/04/25 - 12/11/25

Round trip

Economy

from
$311Fare subject to changes
Updated: 50 minutes ago

Dallas (DFW)to

Grand Cayman (GCM)
12/16/25 - 12/23/25

Round trip

Economy

from
$502Fare subject to changes
Updated: 33 minutes ago

Chicago (ORD)to

Grand Cayman (GCM)
11/26/25 - 12/01/25

Round trip

Economy

from
$482Fare subject to changes
Updated: 12 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
11/08/25 - 11/13/25

Round trip

Economy

from
$524Fare subject to changes
Updated: 5 hours ago

Detroit (DTW)to

Grand Cayman (GCM)
01/07/26 - 01/14/26

Round trip

Economy

from
$650Fare subject to changes
Updated: 40 minutes ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Grand Cayman from **Flights.FromLowestPrice***
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Grand Cayman routes with American Airlines