American Airlines flights from Denver to Saint Louis

Recent searches for flights from Denver to Saint Louis

Aug 2026
From$872*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$325*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$325*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $325
cmp-daily-histogram-bars-legend-max-price-aria-label $872
Displaying fares for August-2026
  • DEN–STL, 08/29/26 – 09/05/26: From $872
    29

    Sa

    AUG

  • DEN–STL, 08/30/26 – 09/06/26: From $872
    30

    Su

  • DEN–STL, 08/31/26 – 09/07/26: From $872
    31

    Mo

  • DEN–STL, 09/01/26 – 09/08/26: From $872
    01

    Tu

    SEP

  • DEN–STL, 09/02/26 – 09/09/26: From $872
    02

    We

  • DEN–STL, 09/03/26 – 09/10/26: From $872
    03

    Th

  • DEN–STL, 09/04/26 – 09/11/26: From $642
    04

    Fr

  • DEN–STL, 09/05/26 – 09/12/26: From $642
    05

    Sa

  • DEN–STL, 09/06/26 – 09/13/26: From $642
    06

    Su

  • DEN–STL, 09/07/26 – 09/14/26: From $642
    07

    Mo

  • DEN–STL, 09/08/26 – 09/15/26: From $642
    08

    Tu

  • DEN–STL, 09/09/26 – 09/16/26: From $642
    09

    We

  • DEN–STL, 09/10/26 – 09/17/26: From $642
    10

    Th

  • DEN–STL, 09/11/26 – 09/18/26: From $401
    11

    Fr

  • DEN–STL, 09/12/26 – 09/19/26: From $401
    12

    Sa

  • DEN–STL, 09/13/26 – 09/20/26: From $447
    13

    Su

  • DEN–STL, 09/14/26 – 09/21/26: From $401
    14

    Mo

  • DEN–STL, 09/15/26 – 09/22/26: From $401
    15

    Tu

  • DEN–STL, 09/16/26 – 09/23/26: From $401
    16

    We

  • DEN–STL, 09/17/26 – 09/24/26: From $504
    17

    Th

  • DEN–STL, 09/18/26 – 09/25/26: From $325
    18

    Fr

  • DEN–STL, 09/19/26 – 09/26/26: From $325
    19

    Sa

  • DEN–STL, 09/20/26 – 09/27/26: From $417
    20

    Su

  • DEN–STL, 09/21/26 – 09/28/26: From $371
    21

    Mo

  • DEN–STL, 09/22/26 – 09/29/26: From $325
    22

    Tu

  • DEN–STL, 09/23/26 – 09/30/26: From $325
    23

    We

  • DEN–STL, 09/24/26 – 10/01/26: From $325
    24

    Th

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Fr

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Sa

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Su

  • DEN–STL, 09/28/26 – 10/05/26: From $371
    28

    Mo

    • range$325-$872

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Denver to Saint Louis flights

    $
    keyboard_arrow_down

    Denver (DEN)to

    Saint Louis (STL)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    10/30/26 - 11/06/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    Denver (DEN)to

    Saint Louis (STL)
    11/05/26 - 11/12/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Denver to Saint Louis

    Looking for lower fares on your trip from Denver to Saint Louis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Denver to Saint Louis