American Airlines flights from Jacksonville to Saint Louis

Recent searches for flights from Jacksonville to Saint Louis

Aug 2026
From$377*
Updated: 22 minutes ago
Round tripIEconomy
Sep 2026
From$343*
Updated: 23 hours ago
Round tripIEconomy
Oct 2026
From$347*
Updated: 22 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $343
cmp-daily-histogram-bars-legend-max-price-aria-label $527
Displaying fares for August-2026
  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Fr

    AUG

  • JAX–STL, 08/29/26 – 09/05/26: From $377
    29

    Sa

  • JAX–STL, 08/30/26 – 09/06/26: From $377
    30

    Su

  • JAX–STL, 08/31/26 – 09/07/26: From $377
    31

    Mo

  • JAX–STL, 09/01/26 – 09/08/26: From $377
    01

    Tu

    SEP

  • JAX–STL, 09/02/26 – 09/09/26: From $377
    02

    We

  • JAX–STL, 09/03/26 – 09/10/26: From $377
    03

    Th

  • JAX–STL, 09/04/26 – 09/11/26: From $377
    04

    Fr

  • JAX–STL, 09/05/26 – 09/12/26: From $377
    05

    Sa

  • JAX–STL, 09/06/26 – 09/13/26: From $377
    06

    Su

  • JAX–STL, 09/07/26 – 09/14/26: From $462
    07

    Mo

  • JAX–STL, 09/08/26 – 09/15/26: From $527
    08

    Tu

  • JAX–STL, 09/09/26 – 09/16/26: From $377
    09

    We

  • JAX–STL, 09/10/26 – 09/17/26: From $377
    10

    Th

  • JAX–STL, 09/11/26 – 09/18/26: From $427
    11

    Fr

  • JAX–STL, 09/12/26 – 09/19/26: From $377
    12

    Sa

  • JAX–STL, 09/13/26 – 09/20/26: From $377
    13

    Su

  • JAX–STL, 09/14/26 – 09/21/26: From $377
    14

    Mo

  • JAX–STL, 09/15/26 – 09/22/26: From $377
    15

    Tu

  • JAX–STL, 09/16/26 – 09/23/26: From $377
    16

    We

  • JAX–STL, 09/17/26 – 09/24/26: From $377
    17

    Th

  • JAX–STL, 09/18/26 – 09/25/26: From $452
    18

    Fr

  • JAX–STL, 09/19/26 – 09/26/26: From $349
    19

    Sa

  • JAX–STL, 09/20/26 – 09/27/26: From $377
    20

    Su

  • JAX–STL, 09/21/26 – 09/28/26: From $349
    21

    Mo

  • JAX–STL, 09/22/26 – 09/29/26: From $348
    22

    Tu

  • JAX–STL, 09/23/26 – 09/30/26: From $348
    23

    We

  • JAX–STL, 09/24/26 – 10/01/26: From $349
    24

    Th

  • JAX–STL, 09/25/26 – 09/27/26: From $343
    25

    Fr

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Sa

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Su

    • range$343-$527

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Jacksonville to Saint Louis flights

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    keyboard_arrow_down

    Jacksonville (JAX)to

    Saint Louis (STL)
    09/25/26 - 09/27/26

    Round trip

    Economy

    from
    $343Fare subject to changes
    Updated: 23 hours ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    Jacksonville (JAX)to

    Saint Louis (STL)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $347Fare subject to changes
    Updated: 22 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Jacksonville to Saint Louis

    Looking for lower fares on your trip from Jacksonville to Saint Louis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Jacksonville to Saint Louis