American Airlines flights from Detroit to Panama City

Recent searches for flights from Detroit to Panama City

Aug 2026
From$887*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$792*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$763*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $887
cmp-daily-histogram-bars-legend-max-price-aria-label $1.5K
Displaying fares for August-2026
  • DTW–PTY: cmp-view-offers-disclaimer. Find Offers
    04

    Tu

    AUG

  • DTW–PTY, 08/05/26 – 08/12/26: From $1,258
    05

    We

  • DTW–PTY, 08/06/26 – 08/13/26: From $1,253
    06

    Th

  • DTW–PTY: cmp-view-offers-disclaimer. Find Offers
    07

    Fr

  • DTW–PTY, 08/08/26 – 08/15/26: From $1,464
    08

    Sa

  • DTW–PTY, 08/09/26 – 08/16/26: From $1,252
    09

    Su

  • DTW–PTY, 08/10/26 – 08/17/26: From $1,077
    10

    Mo

  • DTW–PTY, 08/11/26 – 08/18/26: From $1,052
    11

    Tu

  • DTW–PTY, 08/12/26 – 08/19/26: From $1,053
    12

    We

  • DTW–PTY, 08/13/26 – 08/20/26: From $1,048
    13

    Th

  • DTW–PTY, 08/14/26 – 08/21/26: From $1,052
    14

    Fr

  • DTW–PTY, 08/15/26 – 08/22/26: From $1,205
    15

    Sa

  • DTW–PTY, 08/16/26 – 08/23/26: From $1,178
    16

    Su

  • DTW–PTY, 08/17/26 – 08/24/26: From $961
    17

    Mo

  • DTW–PTY, 08/18/26 – 08/25/26: From $932
    18

    Tu

  • DTW–PTY, 08/19/26 – 08/26/26: From $937
    19

    We

  • DTW–PTY, 08/20/26 – 08/27/26: From $932
    20

    Th

  • DTW–PTY, 08/21/26 – 08/28/26: From $932
    21

    Fr

  • DTW–PTY, 08/22/26 – 08/29/26: From $982
    22

    Sa

  • DTW–PTY, 08/23/26 – 08/30/26: From $1,241
    23

    Su

  • DTW–PTY, 08/24/26 – 08/31/26: From $916
    24

    Mo

  • DTW–PTY, 08/25/26 – 09/01/26: From $887
    25

    Tu

  • DTW–PTY, 08/26/26 – 09/02/26: From $892
    26

    We

  • DTW–PTY, 08/27/26 – 09/03/26: From $887
    27

    Th

  • DTW–PTY, 08/28/26 – 09/04/26: From $887
    28

    Fr

  • DTW–PTY, 08/29/26 – 09/05/26: From $937
    29

    Sa

  • DTW–PTY, 08/30/26 – 09/06/26: From $992
    30

    Su

  • DTW–PTY, 08/31/26 – 09/07/26: From $966
    31

    Mo

  • DTW–PTY, 09/01/26 – 09/08/26: From $887
    01

    Tu

    SEP

  • DTW–PTY, 09/02/26 – 09/09/26: From $892
    02

    We

  • DTW–PTY, 09/03/26 – 09/10/26: From $887
    03

    Th

    • range$887-$1,464

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Panama City flights

    $
    keyboard_arrow_down

    Detroit (DTW)to

    Panama City (PTY)
    11/12/26 - 11/19/26

    Round trip

    Economy

    from
    $733Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    11/26/26 - 12/03/26

    Round trip

    Economy

    from
    $733Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    11/05/26 - 11/12/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    Panama City (PTY)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $737Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Detroit to Panama City

    Looking for lower fares on your trip from Detroit to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Detroit to Panama City