American Airlines flights from San Francisco to Panama City

Recent searches for flights from San Francisco to Panama City

Aug 2026
From$1,066*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$861*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$831*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $861
cmp-daily-histogram-bars-legend-max-price-aria-label $1.3K
Displaying fares for August-2026
  • SFO–PTY, 08/24/26 – 08/31/26: From $1,081
    24

    Mo

    AUG

  • SFO–PTY, 08/25/26 – 09/01/26: From $1,081
    25

    Tu

  • SFO–PTY, 08/26/26 – 09/02/26: From $1,090
    26

    We

  • SFO–PTY, 08/27/26 – 09/03/26: From $1,070
    27

    Th

  • SFO–PTY, 08/28/26 – 09/04/26: From $1,066
    28

    Fr

  • SFO–PTY, 08/29/26 – 09/05/26: From $1,066
    29

    Sa

  • SFO–PTY, 08/30/26 – 09/06/26: From $1,121
    30

    Su

  • SFO–PTY, 08/31/26 – 09/07/26: From $1,086
    31

    Mo

  • SFO–PTY, 09/01/26 – 09/08/26: From $1,036
    01

    Tu

    SEP

  • SFO–PTY, 09/02/26 – 09/09/26: From $1,041
    02

    We

  • SFO–PTY, 09/03/26 – 09/10/26: From $1,331
    03

    Th

  • SFO–PTY, 09/04/26 – 09/11/26: From $1,082
    04

    Fr

  • SFO–PTY, 09/05/26 – 09/12/26: From $1,082
    05

    Sa

  • SFO–PTY, 09/06/26 – 09/13/26: From $1,037
    06

    Su

  • SFO–PTY, 09/07/26 – 09/14/26: From $984
    07

    Mo

  • SFO–PTY, 09/08/26 – 09/15/26: From $988
    08

    Tu

  • SFO–PTY, 09/09/26 – 09/16/26: From $989
    09

    We

  • SFO–PTY, 09/10/26 – 09/17/26: From $984
    10

    Th

  • SFO–PTY, 09/11/26 – 09/18/26: From $984
    11

    Fr

  • SFO–PTY, 09/12/26 – 09/19/26: From $984
    12

    Sa

  • SFO–PTY, 09/13/26 – 09/20/26: From $989
    13

    Su

  • SFO–PTY, 09/14/26 – 09/21/26: From $912
    14

    Mo

  • SFO–PTY, 09/15/26 – 09/22/26: From $912
    15

    Tu

  • SFO–PTY, 09/16/26 – 09/23/26: From $921
    16

    We

  • SFO–PTY, 09/17/26 – 09/24/26: From $912
    17

    Th

  • SFO–PTY, 09/18/26 – 09/25/26: From $912
    18

    Fr

  • SFO–PTY, 09/19/26 – 09/26/26: From $912
    19

    Sa

  • SFO–PTY, 09/20/26 – 09/27/26: From $917
    20

    Su

  • SFO–PTY, 09/21/26 – 09/28/26: From $861
    21

    Mo

  • SFO–PTY, 09/22/26 – 09/29/26: From $861
    22

    Tu

  • SFO–PTY, 09/23/26 – 09/30/26: From $866
    23

    We

    • range$861-$1,331

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Francisco to Panama City flights

    $
    keyboard_arrow_down

    San Francisco (SFO)to

    Panama City (PTY)
    10/26/26 - 11/02/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    10/16/26 - 10/23/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    12/04/26 - 12/11/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    11/13/26 - 11/20/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    San Francisco (SFO)to

    Panama City (PTY)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $831Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Francisco to Panama City

    Looking for lower fares on your trip from San Francisco to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from San Francisco to Panama City