American Airlines flights from Saint Louis to Panama City

Recent searches for flights from Saint Louis to Panama City

Aug 2026
From$683*
Updated: 10 hours ago
Round tripIEconomy
Sep 2026
From$625*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$625*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $629
cmp-daily-histogram-bars-legend-max-price-aria-label $1.2K
Displaying fares for August-2026
  • STL–PTY: cmp-view-offers-disclaimer. Find Offers
    04

    Tu

    AUG

  • STL–PTY, 08/05/26 – 08/12/26: From $861
    05

    We

  • STL–PTY, 08/06/26 – 08/13/26: From $852
    06

    Th

  • STL–PTY: cmp-view-offers-disclaimer. Find Offers
    07

    Fr

  • STL–PTY, 08/08/26 – 08/15/26: From $1,210
    08

    Sa

  • STL–PTY, 08/09/26 – 08/16/26: From $881
    09

    Su

  • STL–PTY, 08/10/26 – 08/17/26: From $863
    10

    Mo

  • STL–PTY, 08/11/26 – 08/18/26: From $781
    11

    Tu

  • STL–PTY, 08/12/26 – 08/19/26: From $790
    12

    We

  • STL–PTY, 08/13/26 – 08/20/26: From $785
    13

    Th

  • STL–PTY, 08/14/26 – 08/21/26: From $785
    14

    Fr

  • STL–PTY, 08/15/26 – 08/22/26: From $930
    15

    Sa

  • STL–PTY, 08/16/26 – 08/23/26: From $840
    16

    Su

  • STL–PTY, 08/17/26 – 08/24/26: From $775
    17

    Mo

  • STL–PTY, 08/18/26 – 08/25/26: From $741
    18

    Tu

  • STL–PTY, 08/19/26 – 08/26/26: From $746
    19

    We

  • STL–PTY, 08/20/26 – 08/27/26: From $741
    20

    Th

  • STL–PTY, 08/21/26 – 08/28/26: From $741
    21

    Fr

  • STL–PTY, 08/22/26 – 08/29/26: From $801
    22

    Sa

  • STL–PTY, 08/23/26 – 08/30/26: From $909
    23

    Su

  • STL–PTY, 08/24/26 – 08/31/26: From $709
    24

    Mo

  • STL–PTY, 08/25/26 – 09/01/26: From $683
    25

    Tu

  • STL–PTY, 08/26/26 – 09/02/26: From $688
    26

    We

  • STL–PTY, 08/27/26 – 09/03/26: From $683
    27

    Th

  • STL–PTY, 08/28/26 – 09/04/26: From $687
    28

    Fr

  • STL–PTY, 08/29/26 – 09/05/26: From $735
    29

    Sa

  • STL–PTY, 08/30/26 – 09/06/26: From $794
    30

    Su

  • STL–PTY, 08/31/26 – 09/07/26: From $701
    31

    Mo

  • STL–PTY, 09/01/26 – 09/08/26: From $629
    01

    Tu

    SEP

  • STL–PTY, 09/02/26 – 09/09/26: From $634
    02

    We

  • STL–PTY, 09/03/26 – 09/10/26: From $667
    03

    Th

    • range$629-$1,210

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to Panama City flights

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    Saint Louis (STL)to

    Panama City (PTY)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    09/10/26 - 09/17/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    09/24/26 - 10/01/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    10/01/26 - 10/08/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    10/02/26 - 10/09/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    Saint Louis (STL)to

    Panama City (PTY)
    09/17/26 - 09/24/26

    Round trip

    Economy

    from
    $625Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to Panama City

    Looking for lower fares on your trip from Saint Louis to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Saint Louis to Panama City