American Airlines flights from Myrtle Beach to San Francisco

Recent searches for flights from Myrtle Beach to San Francisco

Aug 2026
From$568*
Updated: 20 minutes ago
Round tripIEconomy
Sep 2026
From$337*
Updated: 20 minutes ago
Round tripIEconomy
Oct 2026
From$337*
Updated: 20 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $337
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • MYR–SFO, 08/16/26 – 08/23/26: From $1,108
    16

    Su

    AUG

  • MYR–SFO, 08/17/26 – 08/24/26: From $1,003
    17

    Mo

  • MYR–SFO, 08/18/26 – 08/25/26: From $827
    18

    Tu

  • MYR–SFO, 08/19/26 – 08/26/26: From $914
    19

    We

  • MYR–SFO, 08/20/26 – 08/27/26: From $984
    20

    Th

  • MYR–SFO, 08/21/26 – 08/28/26: From $974
    21

    Fr

  • MYR–SFO, 08/22/26 – 08/29/26: From $737
    22

    Sa

  • MYR–SFO, 08/23/26 – 08/30/26: From $847
    23

    Su

  • MYR–SFO, 08/24/26 – 08/31/26: From $773
    24

    Mo

  • MYR–SFO, 08/25/26 – 09/01/26: From $712
    25

    Tu

  • MYR–SFO, 08/26/26 – 09/02/26: From $712
    26

    We

  • MYR–SFO, 08/27/26 – 09/03/26: From $932
    27

    Th

  • MYR–SFO, 08/28/26 – 09/04/26: From $930
    28

    Fr

  • MYR–SFO, 08/29/26 – 09/05/26: From $568
    29

    Sa

  • MYR–SFO, 08/30/26 – 09/06/26: From $578
    30

    Su

  • MYR–SFO, 08/31/26 – 09/07/26: From $568
    31

    Mo

  • MYR–SFO, 09/01/26 – 09/08/26: From $467
    01

    Tu

    SEP

  • MYR–SFO, 09/02/26 – 09/09/26: From $467
    02

    We

  • MYR–SFO, 09/03/26 – 09/10/26: From $568
    03

    Th

  • MYR–SFO, 09/04/26 – 09/11/26: From $490
    04

    Fr

  • MYR–SFO, 09/05/26 – 09/12/26: From $380
    05

    Sa

  • MYR–SFO, 09/06/26 – 09/13/26: From $554
    06

    Su

  • MYR–SFO, 09/07/26 – 09/14/26: From $833
    07

    Mo

  • MYR–SFO, 09/08/26 – 09/15/26: From $763
    08

    Tu

  • MYR–SFO, 09/09/26 – 09/16/26: From $443
    09

    We

  • MYR–SFO, 09/10/26 – 09/17/26: From $478
    10

    Th

  • MYR–SFO, 09/11/26 – 09/18/26: From $538
    11

    Fr

  • MYR–SFO, 09/12/26 – 09/19/26: From $384
    12

    Sa

  • MYR–SFO: cmp-view-offers-disclaimer. Find Offers
    13

    Su

  • MYR–SFO: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

  • MYR–SFO, 09/15/26 – 09/22/26: From $337
    15

    Tu

    • range$337-$1,108

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to San Francisco flights

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    Myrtle Beach (MYR)to

    San Francisco (SFO)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    09/23/26 - 09/30/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    11/05/26 - 11/12/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    Myrtle Beach (MYR)to

    San Francisco (SFO)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 20 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to San Francisco

    Looking for lower fares on your trip from Myrtle Beach to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Myrtle Beach to San Francisco