American Airlines flights from Portland, OR to Buffalo

Recent searches for flights from Portland, OR to Buffalo

Sep 2026
From$558*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$245*
Updated: 2 hours ago
Round tripIEconomy
Nov 2026
From$245*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $377
cmp-daily-histogram-bars-legend-max-price-aria-label $850
Displaying fares for September-2026
  • PDX–BUF: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • PDX–BUF, 09/15/26 – 09/22/26: From $569
    15

    Tu

  • PDX–BUF, 09/16/26 – 09/23/26: From $850
    16

    We

  • PDX–BUF, 09/17/26 – 09/24/26: From $699
    17

    Th

  • PDX–BUF, 09/18/26 – 09/25/26: From $699
    18

    Fr

  • PDX–BUF, 09/19/26 – 09/26/26: From $569
    19

    Sa

  • PDX–BUF, 09/20/26 – 09/27/26: From $699
    20

    Su

  • PDX–BUF, 09/21/26 – 09/28/26: From $751
    21

    Mo

  • PDX–BUF, 09/22/26 – 09/29/26: From $569
    22

    Tu

  • PDX–BUF, 09/23/26 – 09/30/26: From $569
    23

    We

  • PDX–BUF, 09/24/26 – 10/01/26: From $663
    24

    Th

  • PDX–BUF, 09/25/26 – 10/02/26: From $663
    25

    Fr

  • PDX–BUF, 09/26/26 – 10/03/26: From $569
    26

    Sa

  • PDX–BUF, 09/27/26 – 10/04/26: From $663
    27

    Su

  • PDX–BUF, 09/28/26 – 10/05/26: From $715
    28

    Mo

  • PDX–BUF, 09/29/26 – 10/06/26: From $558
    29

    Tu

  • PDX–BUF, 09/30/26 – 10/07/26: From $558
    30

    We

  • PDX–BUF, 10/01/26 – 10/08/26: From $642
    01

    Th

    OCT

  • PDX–BUF, 10/02/26 – 10/09/26: From $623
    02

    Fr

  • PDX–BUF, 10/03/26 – 10/10/26: From $574
    03

    Sa

  • PDX–BUF, 10/04/26 – 10/11/26: From $663
    04

    Su

  • PDX–BUF, 10/05/26 – 10/12/26: From $488
    05

    Mo

  • PDX–BUF, 10/06/26 – 10/13/26: From $377
    06

    Tu

  • PDX–BUF, 10/07/26 – 10/14/26: From $460
    07

    We

  • PDX–BUF, 10/08/26 – 10/15/26: From $636
    08

    Th

  • PDX–BUF, 10/09/26 – 10/16/26: From $505
    09

    Fr

  • PDX–BUF, 10/10/26 – 10/17/26: From $510
    10

    Sa

  • PDX–BUF, 10/11/26 – 10/18/26: From $591
    11

    Su

  • PDX–BUF: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • PDX–BUF: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$377-$850

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, OR to Buffalo flights

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    keyboard_arrow_down

    Portland, OR (PDX)to

    Buffalo (BUF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    Portland, OR (PDX)to

    Buffalo (BUF)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $245Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, OR to Buffalo

    Looking for lower fares on your trip from Portland, OR to Buffalo? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
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    American Airlines flights from Portland, OR to Buffalo