American Airlines flights from San Antonio to Knoxville

Recent searches for flights from San Antonio to Knoxville

Sep 2026
From$452*
Updated: 13 hours ago
Round tripIEconomy
Oct 2026
From$397*
Updated: 13 hours ago
Round tripIEconomy
Nov 2026
From$397*
Updated: 13 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $397
cmp-daily-histogram-bars-legend-max-price-aria-label $1.2K
Displaying fares for September-2026
  • SAT–TYS, 09/13/26 – 09/20/26: From $701
    13

    Su

    SEP

  • SAT–TYS, 09/14/26 – 09/21/26: From $709
    14

    Mo

  • SAT–TYS, 09/15/26 – 09/22/26: From $609
    15

    Tu

  • SAT–TYS, 09/16/26 – 09/23/26: From $609
    16

    We

  • SAT–TYS, 09/17/26 – 09/24/26: From $701
    17

    Th

  • SAT–TYS, 09/18/26 – 09/25/26: From $701
    18

    Fr

  • SAT–TYS, 09/19/26 – 09/26/26: From $598
    19

    Sa

  • SAT–TYS, 09/20/26 – 09/27/26: From $1,246
    20

    Su

  • SAT–TYS, 09/21/26 – 09/28/26: From $650
    21

    Mo

  • SAT–TYS, 09/22/26 – 09/29/26: From $598
    22

    Tu

  • SAT–TYS, 09/23/26 – 09/30/26: From $598
    23

    We

  • SAT–TYS, 09/24/26 – 10/01/26: From $745
    24

    Th

  • SAT–TYS, 09/25/26 – 10/02/26: From $983
    25

    Fr

  • SAT–TYS, 09/26/26 – 10/03/26: From $452
    26

    Sa

  • SAT–TYS, 09/27/26 – 10/04/26: From $745
    27

    Su

  • SAT–TYS, 09/28/26 – 10/05/26: From $503
    28

    Mo

  • SAT–TYS, 09/29/26 – 10/06/26: From $452
    29

    Tu

  • SAT–TYS, 09/30/26 – 10/07/26: From $452
    30

    We

  • SAT–TYS, 10/01/26 – 10/08/26: From $589
    01

    Th

    OCT

  • SAT–TYS, 10/02/26 – 10/09/26: From $538
    02

    Fr

  • SAT–TYS, 10/03/26 – 10/10/26: From $397
    03

    Sa

  • SAT–TYS, 10/04/26 – 10/11/26: From $614
    04

    Su

  • SAT–TYS, 10/05/26 – 10/12/26: From $559
    05

    Mo

  • SAT–TYS, 10/06/26 – 10/13/26: From $473
    06

    Tu

  • SAT–TYS, 10/07/26 – 10/14/26: From $448
    07

    We

  • SAT–TYS, 10/08/26 – 10/15/26: From $778
    08

    Th

  • SAT–TYS, 10/09/26 – 10/16/26: From $778
    09

    Fr

  • SAT–TYS: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

  • SAT–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • SAT–TYS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$397-$1,246

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Antonio to Knoxville flights

    $
    keyboard_arrow_down

    San Antonio (SAT)to

    Knoxville (TYS)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/26/26 - 11/02/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    San Antonio (SAT)to

    Knoxville (TYS)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 13 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Antonio to Knoxville

    Looking for lower fares on your trip from San Antonio to Knoxville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Citi / AAdvantage credit card offer.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from San Antonio to Knoxville