American Airlines flights from Seattle to Knoxville

Recent searches for flights from Seattle to Knoxville

Sep 2026
From$564*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$411*
Updated: 7 hours ago
Round tripIEconomy
Nov 2026
From$411*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $469
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • SEA–TYS, 09/13/26 – 09/20/26: From $1,114
    13

    Su

    SEP

  • SEA–TYS, 09/14/26 – 09/21/26: From $761
    14

    Mo

  • SEA–TYS, 09/15/26 – 09/22/26: From $601
    15

    Tu

  • SEA–TYS, 09/16/26 – 09/23/26: From $601
    16

    We

  • SEA–TYS, 09/17/26 – 09/24/26: From $761
    17

    Th

  • SEA–TYS, 09/18/26 – 09/25/26: From $761
    18

    Fr

  • SEA–TYS, 09/19/26 – 09/26/26: From $601
    19

    Sa

  • SEA–TYS, 09/20/26 – 09/27/26: From $1,110
    20

    Su

  • SEA–TYS, 09/21/26 – 09/28/26: From $740
    21

    Mo

  • SEA–TYS, 09/22/26 – 09/29/26: From $601
    22

    Tu

  • SEA–TYS, 09/23/26 – 09/30/26: From $601
    23

    We

  • SEA–TYS, 09/24/26 – 10/01/26: From $837
    24

    Th

  • SEA–TYS, 09/25/26 – 10/02/26: From $761
    25

    Fr

  • SEA–TYS, 09/26/26 – 10/03/26: From $601
    26

    Sa

  • SEA–TYS, 09/27/26 – 10/04/26: From $703
    27

    Su

  • SEA–TYS, 09/28/26 – 10/05/26: From $567
    28

    Mo

  • SEA–TYS, 09/29/26 – 10/06/26: From $564
    29

    Tu

  • SEA–TYS, 09/30/26 – 10/07/26: From $564
    30

    We

  • SEA–TYS, 10/01/26 – 10/08/26: From $623
    01

    Th

    OCT

  • SEA–TYS, 10/02/26 – 10/09/26: From $567
    02

    Fr

  • SEA–TYS, 10/03/26 – 10/10/26: From $564
    03

    Sa

  • SEA–TYS, 10/04/26 – 10/11/26: From $644
    04

    Su

  • SEA–TYS, 10/05/26 – 10/12/26: From $593
    05

    Mo

  • SEA–TYS, 10/06/26 – 10/13/26: From $469
    06

    Tu

  • SEA–TYS, 10/07/26 – 10/14/26: From $469
    07

    We

  • SEA–TYS, 10/08/26 – 10/15/26: From $633
    08

    Th

  • SEA–TYS, 10/09/26 – 10/16/26: From $614
    09

    Fr

  • SEA–TYS, 10/10/26 – 10/17/26: From $506
    10

    Sa

  • SEA–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • SEA–TYS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$469-$1,114

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Seattle to Knoxville flights

    $
    keyboard_arrow_down

    Seattle (SEA)to

    Knoxville (TYS)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    11/14/26 - 11/21/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Knoxville (TYS)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Seattle to Knoxville

    Looking for lower fares on your trip from Seattle to Knoxville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Seattle to Knoxville