American Airlines flights from Sioux Falls to Key West

Recent searches for flights from Sioux Falls to Key West

Aug 2026
From$394*
Updated: 6 hours ago
Round tripIEconomy
Sep 2026
From$338*
Updated: 6 hours ago
Round tripIEconomy
Oct 2026
From$338*
Updated: 6 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $394
cmp-daily-histogram-bars-legend-max-price-aria-label $785
Displaying fares for August-2026
  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    10

    Mo

    AUG

  • FSD–EYW, 08/11/26 – 08/18/26: From $439
    11

    Tu

  • FSD–EYW, 08/12/26 – 08/19/26: From $525
    12

    We

  • FSD–EYW, 08/13/26 – 08/20/26: From $556
    13

    Th

  • FSD–EYW, 08/14/26 – 08/21/26: From $601
    14

    Fr

  • FSD–EYW, 08/15/26 – 08/22/26: From $439
    15

    Sa

  • FSD–EYW, 08/16/26 – 08/23/26: From $670
    16

    Su

  • FSD–EYW, 08/17/26 – 08/24/26: From $474
    17

    Mo

  • FSD–EYW, 08/18/26 – 08/25/26: From $434
    18

    Tu

  • FSD–EYW, 08/19/26 – 08/26/26: From $434
    19

    We

  • FSD–EYW, 08/20/26 – 08/27/26: From $516
    20

    Th

  • FSD–EYW, 08/21/26 – 08/28/26: From $474
    21

    Fr

  • FSD–EYW, 08/22/26 – 08/29/26: From $434
    22

    Sa

  • FSD–EYW, 08/23/26 – 08/30/26: From $509
    23

    Su

  • FSD–EYW, 08/24/26 – 08/31/26: From $394
    24

    Mo

  • FSD–EYW, 08/25/26 – 09/01/26: From $399
    25

    Tu

  • FSD–EYW, 08/26/26 – 09/02/26: From $394
    26

    We

  • FSD–EYW, 08/27/26 – 09/03/26: From $481
    27

    Th

  • FSD–EYW, 08/28/26 – 09/04/26: From $476
    28

    Fr

  • FSD–EYW, 08/29/26 – 09/05/26: From $394
    29

    Sa

  • FSD–EYW, 08/30/26 – 09/06/26: From $593
    30

    Su

  • FSD–EYW, 08/31/26 – 09/07/26: From $785
    31

    Mo

  • FSD–EYW, 09/01/26 – 09/08/26: From $434
    01

    Tu

    SEP

  • FSD–EYW, 09/02/26 – 09/09/26: From $396
    02

    We

  • FSD–EYW, 09/03/26 – 09/10/26: From $732
    03

    Th

  • FSD–EYW, 09/04/26 – 09/11/26: From $653
    04

    Fr

  • FSD–EYW, 09/05/26 – 09/12/26: From $558
    05

    Sa

  • FSD–EYW, 09/06/26 – 09/13/26: From $712
    06

    Su

  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    07

    Mo

  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    08

    Tu

  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    09

    We

    • range$394-$785

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Sioux Falls to Key West flights

    $
    keyboard_arrow_down

    Sioux Falls (FSD)to

    Key West (EYW)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $343Fare subject to changes
    Updated: 6 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $343Fare subject to changes
    Updated: 6 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Sioux Falls to Key West

    Looking for lower fares on your trip from Sioux Falls to Key West? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Sioux Falls to Key West