American Airlines flights from Sioux Falls to Key West

Recent searches for flights from Sioux Falls to Key West

Sep 2026
From$351*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$338*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$346*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $351
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • FSD–EYW, 09/02/26 – 09/09/26: From $444
    02

    We

    SEP

  • FSD–EYW, 09/03/26 – 09/10/26: From $870
    03

    Th

  • FSD–EYW, 09/04/26 – 09/11/26: From $820
    04

    Fr

  • FSD–EYW, 09/05/26 – 09/12/26: From $547
    05

    Sa

  • FSD–EYW, 09/06/26 – 09/13/26: From $1,036
    06

    Su

  • FSD–EYW, 09/07/26 – 09/14/26: From $752
    07

    Mo

  • FSD–EYW, 09/08/26 – 09/15/26: From $444
    08

    Tu

  • FSD–EYW, 09/09/26 – 09/16/26: From $730
    09

    We

  • FSD–EYW, 09/10/26 – 09/17/26: From $561
    10

    Th

  • FSD–EYW, 09/11/26 – 09/18/26: From $839
    11

    Fr

  • FSD–EYW, 09/12/26 – 09/19/26: From $535
    12

    Sa

  • FSD–EYW, 09/13/26 – 09/20/26: From $1,130
    13

    Su

  • FSD–EYW, 09/14/26 – 09/21/26: From $773
    14

    Mo

  • FSD–EYW, 09/15/26 – 09/22/26: From $449
    15

    Tu

  • FSD–EYW, 09/16/26 – 09/23/26: From $404
    16

    We

  • FSD–EYW, 09/17/26 – 09/24/26: From $662
    17

    Th

  • FSD–EYW, 09/18/26 – 09/25/26: From $662
    18

    Fr

  • FSD–EYW, 09/19/26 – 09/26/26: From $720
    19

    Sa

  • FSD–EYW, 09/20/26 – 09/27/26: From $816
    20

    Su

  • FSD–EYW, 09/21/26 – 09/28/26: From $732
    21

    Mo

  • FSD–EYW, 09/22/26 – 09/29/26: From $404
    22

    Tu

  • FSD–EYW, 09/23/26 – 09/30/26: From $473
    23

    We

  • FSD–EYW, 09/24/26 – 10/01/26: From $697
    24

    Th

  • FSD–EYW, 09/25/26 – 10/02/26: From $679
    25

    Fr

  • FSD–EYW, 09/26/26 – 10/03/26: From $577
    26

    Sa

  • FSD–EYW, 09/27/26 – 10/04/26: From $758
    27

    Su

  • FSD–EYW, 09/28/26 – 10/05/26: From $551
    28

    Mo

  • FSD–EYW, 09/29/26 – 10/06/26: From $351
    29

    Tu

  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    30

    We

  • FSD–EYW: cmp-view-offers-disclaimer. Find Offers
    01

    Th

    OCT

    • range$351-$1,130

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Sioux Falls to Key West flights

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    Sioux Falls (FSD)to

    Key West (EYW)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $346Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    12/08/26 - 12/12/26

    Round trip

    Economy

    from
    $346Fare subject to changes
    Updated: 15 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $351Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $351Fare subject to changes
    Updated: 3 hours ago

    Sioux Falls (FSD)to

    Key West (EYW)
    11/16/26 - 11/23/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Sioux Falls to Key West

    Looking for lower fares on your trip from Sioux Falls to Key West? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Sioux Falls to Key West