American Airlines flights from Buffalo to San Diego

Recent searches for flights from Buffalo to San Diego

Aug 2026
From$327*
Updated: 16 hours ago
Round tripIEconomy
Sep 2026
From$317*
Updated: 16 hours ago
Round tripIEconomy
Oct 2026
From$327*
Updated: 16 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $327
cmp-daily-histogram-bars-legend-max-price-aria-label $1.0K
Displaying fares for August-2026
  • BUF–SAN, 08/02/26 – 08/09/26: From $1,046
    02

    Su

    AUG

  • BUF–SAN, 08/03/26 – 08/10/26: From $1,046
    03

    Mo

  • BUF–SAN, 08/04/26 – 08/11/26: From $953
    04

    Tu

  • BUF–SAN, 08/05/26 – 08/12/26: From $934
    05

    We

  • BUF–SAN, 08/06/26 – 08/25/26: From $634
    06

    Th

  • BUF–SAN, 08/07/26 – 08/24/26: From $707
    07

    Fr

  • BUF–SAN, 08/08/26 – 08/15/26: From $804
    08

    Sa

  • BUF–SAN, 08/09/26 – 08/16/26: From $999
    09

    Su

  • BUF–SAN, 08/10/26 – 08/17/26: From $804
    10

    Mo

  • BUF–SAN, 08/11/26 – 08/25/26: From $604
    11

    Tu

  • BUF–SAN, 08/12/26 – 08/19/26: From $792
    12

    We

  • BUF–SAN, 08/13/26 – 08/20/26: From $804
    13

    Th

  • BUF–SAN, 08/14/26 – 08/21/26: From $804
    14

    Fr

  • BUF–SAN, 08/15/26 – 08/22/26: From $475
    15

    Sa

  • BUF–SAN, 08/16/26 – 08/23/26: From $513
    16

    Su

  • BUF–SAN, 08/17/26 – 08/24/26: From $440
    17

    Mo

  • BUF–SAN, 08/18/26 – 08/25/26: From $440
    18

    Tu

  • BUF–SAN, 08/19/26 – 08/26/26: From $440
    19

    We

  • BUF–SAN, 08/20/26 – 08/27/26: From $440
    20

    Th

  • BUF–SAN, 08/21/26 – 08/28/26: From $440
    21

    Fr

  • BUF–SAN, 08/22/26 – 08/29/26: From $327
    22

    Sa

  • BUF–SAN, 08/23/26 – 08/30/26: From $327
    23

    Su

  • BUF–SAN, 08/24/26 – 08/31/26: From $327
    24

    Mo

  • BUF–SAN, 08/25/26 – 09/01/26: From $327
    25

    Tu

  • BUF–SAN, 08/26/26 – 09/02/26: From $327
    26

    We

  • BUF–SAN, 08/27/26 – 09/03/26: From $440
    27

    Th

  • BUF–SAN, 08/28/26 – 09/04/26: From $327
    28

    Fr

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    Su

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    31

    Mo

  • BUF–SAN, 09/01/26 – 09/08/26: From $327
    01

    Tu

    SEP

    • range$327-$1,046

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Buffalo to San Diego flights

    $
    keyboard_arrow_down

    Buffalo (BUF)to

    San Diego (SAN)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/04/26 - 09/11/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/11/26 - 09/18/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    Buffalo (BUF)to

    San Diego (SAN)
    09/09/26 - 09/14/26

    Round trip

    Economy

    from
    $322Fare subject to changes
    Updated: 16 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Buffalo to San Diego

    Looking for lower fares on your trip from Buffalo to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Buffalo to San Diego