American Airlines flights from Detroit to Destin

Recent searches for flights from Detroit to Destin

Sep 2026
From$469*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$423*
Updated: 8 hours ago
Round tripIEconomy
Nov 2026
From$423*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $423
cmp-daily-histogram-bars-legend-max-price-aria-label $1.3K
Displaying fares for September-2026
  • DTW–VPS, 09/13/26 – 09/20/26: From $1,251
    13

    Su

    SEP

  • DTW–VPS, 09/14/26 – 09/21/26: From $910
    14

    Mo

  • DTW–VPS, 09/15/26 – 09/22/26: From $892
    15

    Tu

  • DTW–VPS, 09/16/26 – 09/23/26: From $892
    16

    We

  • DTW–VPS, 09/17/26 – 09/24/26: From $910
    17

    Th

  • DTW–VPS, 09/18/26 – 09/25/26: From $910
    18

    Fr

  • DTW–VPS, 09/19/26 – 09/26/26: From $680
    19

    Sa

  • DTW–VPS, 09/20/26 – 09/27/26: From $680
    20

    Su

  • DTW–VPS, 09/21/26 – 09/28/26: From $680
    21

    Mo

  • DTW–VPS, 09/22/26 – 09/29/26: From $680
    22

    Tu

  • DTW–VPS, 09/23/26 – 09/30/26: From $680
    23

    We

  • DTW–VPS, 09/24/26 – 10/01/26: From $680
    24

    Th

  • DTW–VPS, 09/25/26 – 10/02/26: From $680
    25

    Fr

  • DTW–VPS, 09/26/26 – 10/03/26: From $469
    26

    Sa

  • DTW–VPS, 09/27/26 – 10/04/26: From $599
    27

    Su

  • DTW–VPS, 09/28/26 – 10/05/26: From $469
    28

    Mo

  • DTW–VPS, 09/29/26 – 10/06/26: From $469
    29

    Tu

  • DTW–VPS, 09/30/26 – 10/07/26: From $573
    30

    We

  • DTW–VPS, 10/01/26 – 10/08/26: From $573
    01

    Th

    OCT

  • DTW–VPS, 10/02/26 – 10/09/26: From $469
    02

    Fr

  • DTW–VPS, 10/03/26 – 10/10/26: From $423
    03

    Sa

  • DTW–VPS, 10/04/26 – 10/11/26: From $589
    04

    Su

  • DTW–VPS, 10/05/26 – 10/12/26: From $423
    05

    Mo

  • DTW–VPS, 10/06/26 – 10/13/26: From $423
    06

    Tu

  • DTW–VPS, 10/07/26 – 10/14/26: From $423
    07

    We

  • DTW–VPS, 10/08/26 – 10/15/26: From $654
    08

    Th

  • DTW–VPS, 10/09/26 – 10/16/26: From $654
    09

    Fr

  • DTW–VPS: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

  • DTW–VPS: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • DTW–VPS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$423-$1,251

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Destin flights

    $
    keyboard_arrow_down

    Detroit (DTW)to

    Destin (VPS)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    10/30/26 - 11/06/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    Detroit (DTW)to

    Destin (VPS)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $423Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Detroit to Destin

    Looking for lower fares on your trip from Detroit to Destin? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Detroit to Destin