American Airlines flights from San Francisco to Destin

Recent searches for flights from San Francisco to Destin

Sep 2026
From$553*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$259*
Updated: 10 hours ago
Round tripIEconomy
Nov 2026
From$259*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $259
cmp-daily-histogram-bars-legend-max-price-aria-label $870
Displaying fares for September-2026
  • SFO–VPS: cmp-view-offers-disclaimer. Find Offers
    16

    We

    SEP

  • SFO–VPS, 09/17/26 – 09/24/26: From $715
    17

    Th

  • SFO–VPS, 09/18/26 – 09/25/26: From $715
    18

    Fr

  • SFO–VPS, 09/19/26 – 09/26/26: From $553
    19

    Sa

  • SFO–VPS, 09/20/26 – 09/27/26: From $715
    20

    Su

  • SFO–VPS, 09/21/26 – 09/28/26: From $722
    21

    Mo

  • SFO–VPS, 09/22/26 – 09/29/26: From $553
    22

    Tu

  • SFO–VPS, 09/23/26 – 09/30/26: From $553
    23

    We

  • SFO–VPS, 09/24/26 – 10/01/26: From $665
    24

    Th

  • SFO–VPS, 09/25/26 – 10/02/26: From $665
    25

    Fr

  • SFO–VPS, 09/26/26 – 10/03/26: From $553
    26

    Sa

  • SFO–VPS, 09/27/26 – 10/04/26: From $870
    27

    Su

  • SFO–VPS, 09/28/26 – 10/05/26: From $665
    28

    Mo

  • SFO–VPS, 09/29/26 – 10/06/26: From $553
    29

    Tu

  • SFO–VPS, 09/30/26 – 10/07/26: From $559
    30

    We

  • SFO–VPS, 10/01/26 – 10/08/26: From $641
    01

    Th

    OCT

  • SFO–VPS, 10/02/26 – 10/09/26: From $591
    02

    Fr

  • SFO–VPS, 10/03/26 – 10/10/26: From $553
    03

    Sa

  • SFO–VPS, 10/04/26 – 10/11/26: From $839
    04

    Su

  • SFO–VPS, 10/05/26 – 10/12/26: From $514
    05

    Mo

  • SFO–VPS, 10/06/26 – 10/13/26: From $361
    06

    Tu

  • SFO–VPS, 10/07/26 – 10/14/26: From $335
    07

    We

  • SFO–VPS, 10/08/26 – 10/15/26: From $454
    08

    Th

  • SFO–VPS, 10/09/26 – 10/16/26: From $522
    09

    Fr

  • SFO–VPS, 10/10/26 – 10/17/26: From $440
    10

    Sa

  • SFO–VPS, 10/11/26 – 10/18/26: From $796
    11

    Su

  • SFO–VPS, 10/12/26 – 10/19/26: From $378
    12

    Mo

  • SFO–VPS, 10/13/26 – 10/20/26: From $259
    13

    Tu

  • SFO–VPS: cmp-view-offers-disclaimer. Find Offers
    14

    We

  • SFO–VPS: cmp-view-offers-disclaimer. Find Offers
    15

    Th

    • range$259-$870

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Francisco to Destin flights

    $
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    San Francisco (SFO)to

    Destin (VPS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    San Francisco (SFO)to

    Destin (VPS)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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