American Airlines flights from Indianapolis to Destin

Recent searches for flights from Indianapolis to Destin

Aug 2026
From$546*
Updated: 7 hours ago
Round tripIEconomy
Sep 2026
From$285*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$285*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $285
cmp-daily-histogram-bars-legend-max-price-aria-label $881
Displaying fares for August-2026
  • IND–VPS: cmp-view-offers-disclaimer. Find Offers
    23

    Su

    AUG

  • IND–VPS, 08/24/26 – 08/31/26: From $675
    24

    Mo

  • IND–VPS, 08/25/26 – 09/01/26: From $675
    25

    Tu

  • IND–VPS, 08/26/26 – 09/02/26: From $675
    26

    We

  • IND–VPS, 08/27/26 – 09/03/26: From $675
    27

    Th

  • IND–VPS, 08/28/26 – 09/04/26: From $675
    28

    Fr

  • IND–VPS, 08/29/26 – 09/05/26: From $675
    29

    Sa

  • IND–VPS, 08/30/26 – 09/06/26: From $546
    30

    Su

  • IND–VPS, 08/31/26 – 09/07/26: From $881
    31

    Mo

  • IND–VPS, 09/01/26 – 09/08/26: From $575
    01

    Tu

    SEP

  • IND–VPS, 09/02/26 – 09/09/26: From $546
    02

    We

  • IND–VPS, 09/03/26 – 09/10/26: From $546
    03

    Th

  • IND–VPS, 09/04/26 – 09/11/26: From $546
    04

    Fr

  • IND–VPS, 09/05/26 – 09/12/26: From $356
    05

    Sa

  • IND–VPS, 09/06/26 – 09/13/26: From $515
    06

    Su

  • IND–VPS, 09/07/26 – 09/14/26: From $356
    07

    Mo

  • IND–VPS, 09/08/26 – 09/15/26: From $356
    08

    Tu

  • IND–VPS, 09/09/26 – 09/16/26: From $285
    09

    We

  • IND–VPS, 09/10/26 – 09/17/26: From $285
    10

    Th

  • IND–VPS, 09/11/26 – 09/18/26: From $306
    11

    Fr

  • IND–VPS, 09/12/26 – 09/19/26: From $306
    12

    Sa

  • IND–VPS, 09/13/26 – 09/20/26: From $565
    13

    Su

  • IND–VPS, 09/14/26 – 09/21/26: From $285
    14

    Mo

  • IND–VPS, 09/15/26 – 09/22/26: From $285
    15

    Tu

  • IND–VPS, 09/16/26 – 09/23/26: From $361
    16

    We

  • IND–VPS, 09/17/26 – 09/24/26: From $285
    17

    Th

  • IND–VPS, 09/18/26 – 09/25/26: From $327
    18

    Fr

  • IND–VPS, 09/19/26 – 09/26/26: From $285
    19

    Sa

  • IND–VPS: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • IND–VPS: cmp-view-offers-disclaimer. Find Offers
    21

    Mo

  • IND–VPS: cmp-view-offers-disclaimer. Find Offers
    22

    Tu

    • range$285-$881

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Indianapolis to Destin flights

    $
    keyboard_arrow_down

    Indianapolis (IND)to

    Destin (VPS)
    10/26/26 - 11/02/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    Indianapolis (IND)to

    Destin (VPS)
    09/19/26 - 09/26/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Indianapolis to Destin

    Looking for lower fares on your trip from Indianapolis to Destin? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Indianapolis to Destin