American Airlines flights from Houston to Santiago

Recent searches for flights from Houston to Santiago

Aug 2026
From$2,135*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$1,310*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$1,185*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $1.4K
cmp-daily-histogram-bars-legend-max-price-aria-label $3.1K
Displaying fares for August-2026
  • IAH–SCL, 08/16/26 – 08/23/26: From $3,085
    16

    Su

    AUG

  • IAH–SCL, 08/17/26 – 08/24/26: From $3,085
    17

    Mo

  • IAH–SCL, 08/18/26 – 08/25/26: From $2,785
    18

    Tu

  • IAH–SCL, 08/19/26 – 08/26/26: From $2,785
    19

    We

  • IAH–SCL, 08/20/26 – 08/27/26: From $2,785
    20

    Th

  • IAH–SCL, 08/21/26 – 08/28/26: From $2,785
    21

    Fr

  • IAH–SCL, 08/22/26 – 08/29/26: From $2,515
    22

    Sa

  • IAH–SCL, 08/23/26 – 08/30/26: From $2,525
    23

    Su

  • IAH–SCL, 08/24/26 – 08/31/26: From $2,525
    24

    Mo

  • IAH–SCL, 08/25/26 – 09/01/26: From $2,525
    25

    Tu

  • IAH–SCL, 08/26/26 – 09/02/26: From $2,525
    26

    We

  • IAH–SCL, 08/27/26 – 09/03/26: From $2,525
    27

    Th

  • IAH–SCL, 08/28/26 – 09/04/26: From $2,525
    28

    Fr

  • IAH–SCL, 08/29/26 – 09/05/26: From $2,305
    29

    Sa

  • IAH–SCL, 08/30/26 – 09/06/26: From $2,135
    30

    Su

  • IAH–SCL, 08/31/26 – 09/07/26: From $2,525
    31

    Mo

  • IAH–SCL, 09/01/26 – 09/08/26: From $2,135
    01

    Tu

    SEP

  • IAH–SCL, 09/02/26 – 09/09/26: From $2,285
    02

    We

  • IAH–SCL, 09/03/26 – 09/10/26: From $2,135
    03

    Th

  • IAH–SCL, 09/04/26 – 09/11/26: From $2,135
    04

    Fr

  • IAH–SCL, 09/05/26 – 09/12/26: From $1,915
    05

    Sa

  • IAH–SCL, 09/06/26 – 09/13/26: From $1,710
    06

    Su

  • IAH–SCL, 09/07/26 – 09/14/26: From $1,710
    07

    Mo

  • IAH–SCL, 09/08/26 – 09/15/26: From $1,710
    08

    Tu

  • IAH–SCL, 09/09/26 – 09/16/26: From $1,710
    09

    We

  • IAH–SCL, 09/10/26 – 09/17/26: From $1,710
    10

    Th

  • IAH–SCL, 09/11/26 – 09/18/26: From $1,710
    11

    Fr

  • IAH–SCL, 09/12/26 – 09/19/26: From $1,515
    12

    Sa

  • IAH–SCL, 09/13/26 – 09/20/26: From $1,435
    13

    Su

  • IAH–SCL, 09/14/26 – 09/21/26: From $1,435
    14

    Mo

  • IAH–SCL, 09/15/26 – 09/22/26: From $1,435
    15

    Tu

    • range$1,435-$3,085

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Houston to Santiago flights

    $
    keyboard_arrow_down

    Houston (IAH)to

    Santiago (SCL)
    10/16/26 - 10/23/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/25/26 - 11/01/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/08/26 - 10/15/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    Houston (IAH)to

    Santiago (SCL)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $1,185Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Houston to Santiago

    Looking for lower fares on your trip from Houston to Santiago? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Houston to Santiago