American Airlines flights from Portland, OR to Santiago

Recent searches for flights from Portland, OR to Santiago

Sep 2026
From$1,052*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$1,052*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$1,052*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $1.1K
cmp-daily-histogram-bars-legend-max-price-aria-label $1.8K
Displaying fares for September-2026
  • PDX–SCL, 09/01/26 – 09/08/26: From $1,358
    01

    Tu

    SEP

  • PDX–SCL, 09/02/26 – 09/09/26: From $1,486
    02

    We

  • PDX–SCL, 09/03/26 – 09/10/26: From $1,253
    03

    Th

  • PDX–SCL, 09/04/26 – 09/11/26: From $1,734
    04

    Fr

  • PDX–SCL, 09/05/26 – 09/12/26: From $1,600
    05

    Sa

  • PDX–SCL, 09/06/26 – 09/13/26: From $1,734
    06

    Su

  • PDX–SCL, 09/07/26 – 09/14/26: From $1,358
    07

    Mo

  • PDX–SCL, 09/08/26 – 09/15/26: From $1,358
    08

    Tu

  • PDX–SCL, 09/09/26 – 09/16/26: From $1,052
    09

    We

  • PDX–SCL, 09/10/26 – 09/17/26: From $1,486
    10

    Th

  • PDX–SCL, 09/11/26 – 09/18/26: From $1,734
    11

    Fr

  • PDX–SCL, 09/12/26 – 09/19/26: From $1,763
    12

    Sa

  • PDX–SCL, 09/13/26 – 09/20/26: From $1,664
    13

    Su

  • PDX–SCL, 09/14/26 – 09/21/26: From $1,635
    14

    Mo

  • PDX–SCL, 09/15/26 – 09/22/26: From $1,543
    15

    Tu

  • PDX–SCL, 09/16/26 – 09/23/26: From $1,171
    16

    We

  • PDX–SCL, 09/17/26 – 09/24/26: From $1,253
    17

    Th

  • PDX–SCL, 09/18/26 – 09/25/26: From $1,253
    18

    Fr

  • PDX–SCL, 09/19/26 – 09/26/26: From $1,830
    19

    Sa

  • PDX–SCL, 09/20/26 – 09/27/26: From $1,635
    20

    Su

  • PDX–SCL, 09/21/26 – 09/28/26: From $1,253
    21

    Mo

  • PDX–SCL, 09/22/26 – 09/29/26: From $1,171
    22

    Tu

  • PDX–SCL, 09/23/26 – 09/30/26: From $1,171
    23

    We

  • PDX–SCL, 09/24/26 – 10/01/26: From $1,253
    24

    Th

  • PDX–SCL, 09/25/26 – 10/02/26: From $1,486
    25

    Fr

  • PDX–SCL, 09/26/26 – 10/03/26: From $1,318
    26

    Sa

  • PDX–SCL, 09/27/26 – 10/04/26: From $1,052
    27

    Su

  • PDX–SCL, 09/28/26 – 10/05/26: From $1,052
    28

    Mo

  • PDX–SCL, 09/29/26 – 10/06/26: From $1,052
    29

    Tu

  • PDX–SCL, 09/30/26 – 10/07/26: From $1,052
    30

    We

    • range$1,052-$1,830

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, OR to Santiago flights

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    Portland, OR (PDX)to

    Santiago (SCL)
    12/07/26 - 12/14/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/04/26 - 12/11/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/10/26 - 12/17/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/06/26 - 12/13/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    Portland, OR (PDX)to

    Santiago (SCL)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $1,047Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, OR to Santiago

    Looking for lower fares on your trip from Portland, OR to Santiago? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Portland, OR to Santiago