American Airlines flights from San Diego to Santiago

Recent searches for flights from San Diego to Santiago

Sep 2026
From$1,050*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$868*
Updated: 10 hours ago
Round tripIEconomy
Nov 2026
From$868*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $1.1K
cmp-daily-histogram-bars-legend-max-price-aria-label $2.2K
Displaying fares for September-2026
  • SAN–SCL, 09/05/26 – 09/12/26: From $1,886
    05

    Sa

    SEP

  • SAN–SCL, 09/06/26 – 09/13/26: From $1,441
    06

    Su

  • SAN–SCL, 09/07/26 – 09/14/26: From $1,418
    07

    Mo

  • SAN–SCL, 09/08/26 – 09/15/26: From $1,160
    08

    Tu

  • SAN–SCL, 09/09/26 – 09/16/26: From $1,050
    09

    We

  • SAN–SCL, 09/10/26 – 09/17/26: From $1,050
    10

    Th

  • SAN–SCL, 09/11/26 – 09/18/26: From $1,418
    11

    Fr

  • SAN–SCL, 09/12/26 – 09/19/26: From $1,435
    12

    Sa

  • SAN–SCL, 09/13/26 – 09/20/26: From $1,813
    13

    Su

  • SAN–SCL, 09/14/26 – 09/21/26: From $1,418
    14

    Mo

  • SAN–SCL, 09/15/26 – 09/22/26: From $1,165
    15

    Tu

  • SAN–SCL, 09/16/26 – 09/23/26: From $1,145
    16

    We

  • SAN–SCL, 09/17/26 – 09/24/26: From $1,571
    17

    Th

  • SAN–SCL, 09/18/26 – 09/25/26: From $1,886
    18

    Fr

  • SAN–SCL, 09/19/26 – 09/26/26: From $2,248
    19

    Sa

  • SAN–SCL, 09/20/26 – 09/27/26: From $1,906
    20

    Su

  • SAN–SCL, 09/21/26 – 09/28/26: From $1,165
    21

    Mo

  • SAN–SCL, 09/22/26 – 09/29/26: From $1,096
    22

    Tu

  • SAN–SCL, 09/23/26 – 09/30/26: From $1,145
    23

    We

  • SAN–SCL, 09/24/26 – 10/01/26: From $1,513
    24

    Th

  • SAN–SCL, 09/25/26 – 10/02/26: From $1,886
    25

    Fr

  • SAN–SCL, 09/26/26 – 10/03/26: From $1,308
    26

    Sa

  • SAN–SCL, 09/27/26 – 10/04/26: From $1,290
    27

    Su

  • SAN–SCL, 09/28/26 – 10/05/26: From $1,213
    28

    Mo

  • SAN–SCL, 09/29/26 – 10/06/26: From $1,160
    29

    Tu

  • SAN–SCL, 09/30/26 – 10/07/26: From $1,145
    30

    We

  • SAN–SCL, 10/01/26 – 10/08/26: From $2,141
    01

    Th

    OCT

  • SAN–SCL, 10/02/26 – 10/09/26: From $1,308
    02

    Fr

  • SAN–SCL, 10/03/26 – 10/10/26: From $1,213
    03

    Sa

  • SAN–SCL, 10/04/26 – 10/11/26: From $1,240
    04

    Su

    • range$1,050-$2,248

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Diego to Santiago flights

    $
    keyboard_arrow_down

    San Diego (SAN)to

    Santiago (SCL)
    02/03/27 - 02/13/27

    Round trip

    Economy

    from
    $818Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/06/26 - 12/13/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/07/26 - 12/14/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    12/10/26 - 12/17/26

    Round trip

    Economy

    from
    $868Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Diego to Santiago

    Looking for lower fares on your trip from San Diego to Santiago? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from San Diego to Santiago