American Airlines flights from San Diego to Santiago

Recent searches for flights from San Diego to Santiago

Aug 2026
From$825*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$830*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$825*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $825
cmp-daily-histogram-bars-legend-max-price-aria-label $1.8K
Displaying fares for August-2026
  • SAN–SCL, 08/15/26 – 08/22/26: From $1,462
    15

    Sa

    AUG

  • SAN–SCL, 08/16/26 – 08/23/26: From $1,546
    16

    Su

  • SAN–SCL, 08/17/26 – 08/24/26: From $840
    17

    Mo

  • SAN–SCL, 08/18/26 – 08/25/26: From $825
    18

    Tu

  • SAN–SCL, 08/19/26 – 08/26/26: From $825
    19

    We

  • SAN–SCL, 08/20/26 – 08/27/26: From $825
    20

    Th

  • SAN–SCL, 08/21/26 – 08/28/26: From $1,415
    21

    Fr

  • SAN–SCL, 08/22/26 – 08/29/26: From $1,328
    22

    Sa

  • SAN–SCL, 08/23/26 – 08/30/26: From $880
    23

    Su

  • SAN–SCL, 08/24/26 – 08/31/26: From $825
    24

    Mo

  • SAN–SCL, 08/25/26 – 09/01/26: From $825
    25

    Tu

  • SAN–SCL, 08/26/26 – 09/02/26: From $825
    26

    We

  • SAN–SCL, 08/27/26 – 09/03/26: From $935
    27

    Th

  • SAN–SCL, 08/28/26 – 09/04/26: From $875
    28

    Fr

  • SAN–SCL, 08/29/26 – 09/05/26: From $875
    29

    Sa

  • SAN–SCL, 08/30/26 – 09/06/26: From $1,005
    30

    Su

  • SAN–SCL, 08/31/26 – 09/07/26: From $1,073
    31

    Mo

  • SAN–SCL, 09/01/26 – 09/08/26: From $954
    01

    Tu

    SEP

  • SAN–SCL, 09/02/26 – 09/09/26: From $1,750
    02

    We

  • SAN–SCL, 09/03/26 – 09/10/26: From $1,368
    03

    Th

  • SAN–SCL, 09/04/26 – 09/11/26: From $1,531
    04

    Fr

  • SAN–SCL, 09/05/26 – 09/12/26: From $1,283
    05

    Sa

  • SAN–SCL, 09/06/26 – 09/13/26: From $1,025
    06

    Su

  • SAN–SCL, 09/07/26 – 09/14/26: From $830
    07

    Mo

  • SAN–SCL, 09/08/26 – 09/15/26: From $830
    08

    Tu

  • SAN–SCL, 09/09/26 – 09/16/26: From $830
    09

    We

  • SAN–SCL, 09/10/26 – 09/17/26: From $844
    10

    Th

  • SAN–SCL, 09/11/26 – 09/18/26: From $1,078
    11

    Fr

  • SAN–SCL, 09/12/26 – 09/19/26: From $844
    12

    Sa

  • SAN–SCL, 09/13/26 – 09/20/26: From $1,010
    13

    Su

  • SAN–SCL, 09/14/26 – 09/21/26: From $830
    14

    Mo

    • range$825-$1,750

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Diego to Santiago flights

    $
    keyboard_arrow_down

    San Diego (SAN)to

    Santiago (SCL)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/26/26 - 11/02/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    San Diego (SAN)to

    Santiago (SCL)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $825Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Diego to Santiago

    Looking for lower fares on your trip from San Diego to Santiago? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from San Diego to Santiago