American Airlines flights from Manchester to Key West

Recent searches for flights from Manchester to Key West

Aug 2026
From$425*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$321*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$321*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $373
cmp-daily-histogram-bars-legend-max-price-aria-label $1.0K
Displaying fares for August-2026
  • MHT–EYW, 08/22/26 – 08/29/26: From $454
    22

    Sa

    AUG

  • MHT–EYW, 08/23/26 – 08/30/26: From $749
    23

    Su

  • MHT–EYW, 08/24/26 – 08/31/26: From $545
    24

    Mo

  • MHT–EYW, 08/25/26 – 09/01/26: From $425
    25

    Tu

  • MHT–EYW, 08/26/26 – 09/02/26: From $425
    26

    We

  • MHT–EYW, 08/27/26 – 09/03/26: From $545
    27

    Th

  • MHT–EYW, 08/28/26 – 09/04/26: From $545
    28

    Fr

  • MHT–EYW, 08/29/26 – 09/05/26: From $425
    29

    Sa

  • MHT–EYW, 08/30/26 – 09/06/26: From $585
    30

    Su

  • MHT–EYW, 08/31/26 – 09/07/26: From $903
    31

    Mo

  • MHT–EYW, 09/01/26 – 09/08/26: From $479
    01

    Tu

    SEP

  • MHT–EYW, 09/02/26 – 09/09/26: From $454
    02

    We

  • MHT–EYW, 09/03/26 – 09/10/26: From $545
    03

    Th

  • MHT–EYW, 09/04/26 – 09/11/26: From $545
    04

    Fr

  • MHT–EYW, 09/05/26 – 09/12/26: From $373
    05

    Sa

  • MHT–EYW, 09/06/26 – 09/13/26: From $897
    06

    Su

  • MHT–EYW, 09/07/26 – 09/14/26: From $580
    07

    Mo

  • MHT–EYW, 09/08/26 – 09/15/26: From $425
    08

    Tu

  • MHT–EYW, 09/09/26 – 09/16/26: From $373
    09

    We

  • MHT–EYW, 09/10/26 – 09/17/26: From $585
    10

    Th

  • MHT–EYW, 09/11/26 – 09/18/26: From $433
    11

    Fr

  • MHT–EYW, 09/12/26 – 09/19/26: From $458
    12

    Sa

  • MHT–EYW, 09/13/26 – 09/20/26: From $1,002
    13

    Su

  • MHT–EYW, 09/14/26 – 09/21/26: From $669
    14

    Mo

  • MHT–EYW, 09/15/26 – 09/22/26: From $454
    15

    Tu

  • MHT–EYW, 09/16/26 – 09/23/26: From $373
    16

    We

  • MHT–EYW, 09/17/26 – 09/24/26: From $585
    17

    Th

  • MHT–EYW, 09/18/26 – 09/25/26: From $518
    18

    Fr

  • MHT–EYW: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • MHT–EYW: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • MHT–EYW, 09/21/26 – 09/28/26: From $523
    21

    Mo

    • range$373-$1,002

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Manchester to Key West flights

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    Manchester (MHT)to

    Key West (EYW)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 1 hour ago

    Manchester (MHT)to

    Key West (EYW)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Manchester to Key West

    Looking for lower fares on your trip from Manchester to Key West? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Manchester to Key West