American Airlines flights from Milwaukee to Charleston, SC

Recent searches for flights from Milwaukee to Charleston, SC

Aug 2026
From$589*
Updated: 3 hours ago
Round tripIEconomy
Sep 2026
From$339*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$339*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $339
cmp-daily-histogram-bars-legend-max-price-aria-label $681
Displaying fares for August-2026
  • MKE–CHS, 08/24/26 – 08/31/26: From $681
    24

    Mo

    AUG

  • MKE–CHS, 08/25/26 – 09/01/26: From $589
    25

    Tu

  • MKE–CHS, 08/26/26 – 09/02/26: From $589
    26

    We

  • MKE–CHS, 08/27/26 – 09/03/26: From $681
    27

    Th

  • MKE–CHS, 08/28/26 – 09/04/26: From $681
    28

    Fr

  • MKE–CHS, 08/29/26 – 09/05/26: From $589
    29

    Sa

  • MKE–CHS, 08/30/26 – 09/06/26: From $681
    30

    Su

  • MKE–CHS, 08/31/26 – 09/07/26: From $681
    31

    Mo

  • MKE–CHS, 09/01/26 – 09/08/26: From $574
    01

    Tu

    SEP

  • MKE–CHS, 09/02/26 – 09/09/26: From $574
    02

    We

  • MKE–CHS, 09/03/26 – 09/10/26: From $620
    03

    Th

  • MKE–CHS, 09/04/26 – 09/11/26: From $620
    04

    Fr

  • MKE–CHS, 09/05/26 – 09/12/26: From $454
    05

    Sa

  • MKE–CHS, 09/06/26 – 09/13/26: From $454
    06

    Su

  • MKE–CHS, 09/07/26 – 09/14/26: From $428
    07

    Mo

  • MKE–CHS, 09/08/26 – 09/15/26: From $428
    08

    Tu

  • MKE–CHS, 09/09/26 – 09/16/26: From $365
    09

    We

  • MKE–CHS, 09/10/26 – 09/17/26: From $365
    10

    Th

  • MKE–CHS, 09/11/26 – 09/18/26: From $378
    11

    Fr

  • MKE–CHS, 09/12/26 – 09/19/26: From $365
    12

    Sa

  • MKE–CHS, 09/13/26 – 09/20/26: From $487
    13

    Su

  • MKE–CHS, 09/14/26 – 09/21/26: From $339
    14

    Mo

  • MKE–CHS, 09/15/26 – 09/22/26: From $339
    15

    Tu

  • MKE–CHS, 09/16/26 – 09/23/26: From $339
    16

    We

  • MKE–CHS, 09/17/26 – 09/24/26: From $339
    17

    Th

  • MKE–CHS, 09/18/26 – 09/25/26: From $365
    18

    Fr

  • MKE–CHS, 09/19/26 – 09/26/26: From $339
    19

    Sa

  • MKE–CHS, 09/20/26 – 09/27/26: From $609
    20

    Su

  • MKE–CHS: cmp-view-offers-disclaimer. Find Offers
    21

    Mo

  • MKE–CHS, 09/22/26 – 09/25/26: From $352
    22

    Tu

  • MKE–CHS, 09/23/26 – 09/30/26: From $339
    23

    We

    • range$339-$681

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Milwaukee to Charleston, SC flights

    $
    keyboard_arrow_down

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Milwaukee to Charleston, SC

    Looking for lower fares on your trip from Milwaukee to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Milwaukee to Charleston, SC