American Airlines flights from Milwaukee to Charleston, SC

Recent searches for flights from Milwaukee to Charleston, SC

Sep 2026
From$477*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$391*
Updated: 22 hours ago
Round tripIEconomy
Nov 2026
From$391*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $404
cmp-daily-histogram-bars-legend-max-price-aria-label $747
Displaying fares for September-2026
  • MKE–CHS, 09/13/26 – 09/20/26: From $701
    13

    Su

    SEP

  • MKE–CHS, 09/14/26 – 09/21/26: From $701
    14

    Mo

  • MKE–CHS, 09/15/26 – 09/22/26: From $609
    15

    Tu

  • MKE–CHS, 09/16/26 – 09/23/26: From $609
    16

    We

  • MKE–CHS, 09/17/26 – 09/24/26: From $701
    17

    Th

  • MKE–CHS, 09/18/26 – 09/25/26: From $701
    18

    Fr

  • MKE–CHS, 09/19/26 – 09/26/26: From $609
    19

    Sa

  • MKE–CHS, 09/20/26 – 09/27/26: From $747
    20

    Su

  • MKE–CHS, 09/21/26 – 09/28/26: From $630
    21

    Mo

  • MKE–CHS, 09/22/26 – 09/29/26: From $584
    22

    Tu

  • MKE–CHS, 09/23/26 – 09/30/26: From $584
    23

    We

  • MKE–CHS, 09/24/26 – 10/01/26: From $630
    24

    Th

  • MKE–CHS, 09/25/26 – 10/02/26: From $630
    25

    Fr

  • MKE–CHS, 09/26/26 – 10/03/26: From $584
    26

    Sa

  • MKE–CHS, 09/27/26 – 10/04/26: From $676
    27

    Su

  • MKE–CHS, 09/28/26 – 10/05/26: From $477
    28

    Mo

  • MKE–CHS, 09/29/26 – 10/06/26: From $477
    29

    Tu

  • MKE–CHS, 09/30/26 – 10/07/26: From $477
    30

    We

  • MKE–CHS, 10/01/26 – 10/08/26: From $477
    01

    Th

    OCT

  • MKE–CHS, 10/02/26 – 10/09/26: From $477
    02

    Fr

  • MKE–CHS, 10/03/26 – 10/10/26: From $477
    03

    Sa

  • MKE–CHS, 10/04/26 – 10/11/26: From $457
    04

    Su

  • MKE–CHS, 10/05/26 – 10/12/26: From $417
    05

    Mo

  • MKE–CHS, 10/06/26 – 10/13/26: From $404
    06

    Tu

  • MKE–CHS, 10/07/26 – 10/14/26: From $404
    07

    We

  • MKE–CHS, 10/08/26 – 10/15/26: From $599
    08

    Th

  • MKE–CHS, 10/09/26 – 10/16/26: From $417
    09

    Fr

  • MKE–CHS, 10/10/26 – 10/17/26: From $404
    10

    Sa

  • MKE–CHS: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • MKE–CHS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$404-$747

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Milwaukee to Charleston, SC flights

    $
    keyboard_arrow_down

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 22 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    Milwaukee (MKE)to

    Charleston, SC (CHS)
    11/14/26 - 11/21/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Milwaukee to Charleston, SC

    Looking for lower fares on your trip from Milwaukee to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Citi / AAdvantage credit card offer.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Milwaukee to Charleston, SC