American Airlines flights from Saint Louis to Charleston, SC

Recent searches for flights from Saint Louis to Charleston, SC

Mar 2026
From$456*
Updated: 2 hours ago
Round tripIEconomy
Apr 2026
From$507*
Updated: 17 hours ago
Round tripIEconomy
May 2026
From$246*
Updated: 18 hours ago
Round tripIEconomy
$456
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    • range$456-$844

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to Charleston, SC flights

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    Saint Louis (STL)to

    Charleston, SC (CHS)
    05/19/26 - 05/23/26

    Round trip

    Economy

    from
    $246Fare subject to changes
    Updated: 18 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    05/30/26 - 06/02/26

    Round trip

    Economy

    from
    $272Fare subject to changes
    Updated: 18 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    05/30/26 - 06/03/26

    Round trip

    Economy

    from
    $282Fare subject to changes
    Updated: 21 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    05/18/26 - 05/23/26

    Round trip

    Economy

    from
    $288Fare subject to changes
    Updated: 18 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    06/27/26 - 07/01/26

    Round trip

    Economy

    from
    $317Fare subject to changes
    Updated: 5 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/03/26 - 09/07/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 22 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    06/19/26 - 06/21/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 22 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    05/01/26 - 05/03/26

    Round trip

    Economy

    from
    $416Fare subject to changes
    Updated: 20 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    American Airlines flights from Saint Louis to Charleston, SC

    Earn up to $400 back on your next American Airlines flight plus, 30,000 bonus miles. Terms apply. Opens another site in a new window that may not meet accessibility guidelines.