American Airlines flights from Saint Louis to Charleston, SC

Recent searches for flights from Saint Louis to Charleston, SC

Aug 2026
From$435*
Updated: 46 minutes ago
Round tripIEconomy
Sep 2026
From$227*
Updated: 46 minutes ago
Round tripIEconomy
Oct 2026
From$227*
Updated: 46 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $227
cmp-daily-histogram-bars-legend-max-price-aria-label $537
Displaying fares for August-2026
  • STL–CHS, 08/25/26 – 09/01/26: From $435
    25

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  • STL–CHS, 08/26/26 – 09/02/26: From $435
    26

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  • STL–CHS, 08/27/26 – 09/03/26: From $435
    27

    Th

  • STL–CHS, 08/28/26 – 09/04/26: From $435
    28

    Fr

  • STL–CHS, 08/29/26 – 09/05/26: From $435
    29

    Sa

  • STL–CHS, 08/30/26 – 09/06/26: From $435
    30

    Su

  • STL–CHS, 08/31/26 – 09/07/26: From $537
    31

    Mo

  • STL–CHS, 09/01/26 – 09/08/26: From $435
    01

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    SEP

  • STL–CHS, 09/02/26 – 09/09/26: From $435
    02

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  • STL–CHS, 09/03/26 – 09/10/26: From $435
    03

    Th

  • STL–CHS, 09/04/26 – 09/11/26: From $435
    04

    Fr

  • STL–CHS, 09/05/26 – 09/12/26: From $435
    05

    Sa

  • STL–CHS, 09/06/26 – 09/13/26: From $435
    06

    Su

  • STL–CHS, 09/07/26 – 09/14/26: From $357
    07

    Mo

  • STL–CHS, 09/08/26 – 09/15/26: From $357
    08

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  • STL–CHS, 09/09/26 – 09/16/26: From $357
    09

    We

  • STL–CHS, 09/10/26 – 09/17/26: From $357
    10

    Th

  • STL–CHS, 09/11/26 – 09/18/26: From $376
    11

    Fr

  • STL–CHS, 09/12/26 – 09/19/26: From $357
    12

    Sa

  • STL–CHS, 09/13/26 – 09/20/26: From $427
    13

    Su

  • STL–CHS, 09/14/26 – 09/21/26: From $227
    14

    Mo

  • STL–CHS, 09/15/26 – 09/22/26: From $227
    15

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  • STL–CHS, 09/16/26 – 09/23/26: From $227
    16

    We

  • STL–CHS, 09/17/26 – 09/24/26: From $323
    17

    Th

  • STL–CHS, 09/18/26 – 09/21/26: From $323
    18

    Fr

  • STL–CHS, 09/19/26 – 09/26/26: From $227
    19

    Sa

  • STL–CHS, 09/20/26 – 09/23/26: From $297
    20

    Su

  • STL–CHS, 09/21/26 – 09/28/26: From $227
    21

    Mo

  • STL–CHS: cmp-view-offers-disclaimer. Find Offers
    22

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  • STL–CHS: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • STL–CHS, 09/24/26 – 10/01/26: From $323
    24

    Th

    • range$227-$537

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to Charleston, SC flights

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    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/21/26 - 09/28/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $227Fare subject to changes
    Updated: 46 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to Charleston, SC

    Looking for lower fares on your trip from Saint Louis to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Saint Louis to Charleston, SC