American Airlines flights from Saint Louis to Charleston, SC

Recent searches for flights from Saint Louis to Charleston, SC

Aug 2026
From$251*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$251*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$265*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $251
cmp-daily-histogram-bars-legend-max-price-aria-label $494
Displaying fares for August-2026
  • STL–CHS, 08/05/26 – 08/12/26: From $435
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  • STL–CHS, 08/06/26 – 08/13/26: From $435
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  • STL–CHS, 08/07/26 – 08/14/26: From $435
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  • STL–CHS, 08/08/26 – 08/15/26: From $435
    08

    Sa

  • STL–CHS, 08/09/26 – 08/16/26: From $435
    09

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  • STL–CHS, 08/10/26 – 08/17/26: From $435
    10

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  • STL–CHS, 08/11/26 – 08/18/26: From $435
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  • STL–CHS, 08/12/26 – 08/19/26: From $435
    12

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  • STL–CHS, 08/13/26 – 08/20/26: From $435
    13

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  • STL–CHS, 08/14/26 – 08/21/26: From $435
    14

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  • STL–CHS, 08/15/26 – 08/22/26: From $435
    15

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  • STL–CHS, 08/16/26 – 08/23/26: From $435
    16

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  • STL–CHS, 08/17/26 – 08/24/26: From $435
    17

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  • STL–CHS, 08/18/26 – 08/25/26: From $435
    18

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  • STL–CHS, 08/19/26 – 08/26/26: From $376
    19

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  • STL–CHS, 08/20/26 – 08/27/26: From $376
    20

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  • STL–CHS, 08/21/26 – 08/28/26: From $393
    21

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  • STL–CHS, 08/22/26 – 08/29/26: From $376
    22

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  • STL–CHS, 08/23/26 – 08/30/26: From $393
    23

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  • STL–CHS, 08/24/26 – 08/31/26: From $376
    24

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  • STL–CHS, 08/25/26 – 09/01/26: From $376
    25

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  • STL–CHS, 08/26/26 – 09/02/26: From $265
    26

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  • STL–CHS, 08/27/26 – 09/03/26: From $265
    27

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  • STL–CHS, 08/28/26 – 09/04/26: From $325
    28

    Fr

  • STL–CHS, 08/29/26 – 09/05/26: From $251
    29

    Sa

  • STL–CHS, 08/30/26 – 09/06/26: From $268
    30

    Su

  • STL–CHS, 08/31/26 – 09/07/26: From $494
    31

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  • STL–CHS, 09/01/26 – 09/08/26: From $265
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  • STL–CHS: cmp-view-offers-disclaimer. Find Offers
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  • STL–CHS: cmp-view-offers-disclaimer. Find Offers
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  • STL–CHS, 09/04/26 – 09/11/26: From $323
    04

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    • range$251-$494

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to Charleston, SC flights

    $
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    Saint Louis (STL)to

    Charleston, SC (CHS)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $251Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $251Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/01/26 - 09/08/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/10/26 - 09/17/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    Saint Louis (STL)to

    Charleston, SC (CHS)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $265Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to Charleston, SC

    Looking for lower fares on your trip from Saint Louis to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Saint Louis to Charleston, SC