American Airlines flights from Minneapolis to Charleston, SC

Recent searches for flights from Minneapolis to Charleston, SC

Aug 2026
From$819*
Updated: 6 hours ago
Round tripIEconomy
Sep 2026
From$329*
Updated: 6 hours ago
Round tripIEconomy
Oct 2026
From$329*
Updated: 6 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $329
cmp-daily-histogram-bars-legend-max-price-aria-label $874
Displaying fares for August-2026
  • MSP–CHS, 08/26/26 – 09/02/26: From $838
    26

    We

    AUG

  • MSP–CHS, 08/27/26 – 09/03/26: From $874
    27

    Th

  • MSP–CHS, 08/28/26 – 09/04/26: From $874
    28

    Fr

  • MSP–CHS, 08/29/26 – 09/05/26: From $819
    29

    Sa

  • MSP–CHS, 08/30/26 – 09/06/26: From $874
    30

    Su

  • MSP–CHS, 08/31/26 – 09/07/26: From $874
    31

    Mo

  • MSP–CHS, 09/01/26 – 09/08/26: From $694
    01

    Tu

    SEP

  • MSP–CHS, 09/02/26 – 09/09/26: From $694
    02

    We

  • MSP–CHS, 09/03/26 – 09/10/26: From $694
    03

    Th

  • MSP–CHS, 09/04/26 – 09/11/26: From $694
    04

    Fr

  • MSP–CHS, 09/05/26 – 09/12/26: From $673
    05

    Sa

  • MSP–CHS, 09/06/26 – 09/09/26: From $646
    06

    Su

  • MSP–CHS, 09/07/26 – 09/14/26: From $694
    07

    Mo

  • MSP–CHS, 09/08/26 – 09/15/26: From $436
    08

    Tu

  • MSP–CHS, 09/09/26 – 09/16/26: From $436
    09

    We

  • MSP–CHS, 09/10/26 – 09/17/26: From $436
    10

    Th

  • MSP–CHS, 09/11/26 – 09/18/26: From $457
    11

    Fr

  • MSP–CHS, 09/12/26 – 09/19/26: From $436
    12

    Sa

  • MSP–CHS, 09/13/26 – 09/20/26: From $479
    13

    Su

  • MSP–CHS, 09/14/26 – 09/21/26: From $436
    14

    Mo

  • MSP–CHS, 09/15/26 – 09/22/26: From $343
    15

    Tu

  • MSP–CHS, 09/16/26 – 09/23/26: From $343
    16

    We

  • MSP–CHS, 09/17/26 – 09/24/26: From $474
    17

    Th

  • MSP–CHS, 09/18/26 – 09/25/26: From $379
    18

    Fr

  • MSP–CHS, 09/19/26 – 09/26/26: From $336
    19

    Sa

  • MSP–CHS, 09/20/26 – 09/27/26: From $523
    20

    Su

  • MSP–CHS, 09/21/26 – 09/28/26: From $336
    21

    Mo

  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    22

    Tu

  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    24

    Th

  • MSP–CHS, 09/25/26 – 10/02/26: From $329
    25

    Fr

    • range$329-$874

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Minneapolis to Charleston, SC flights

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    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/04/26 - 11/07/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 10 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $304Fare subject to changes
    Updated: 6 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $304Fare subject to changes
    Updated: 6 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Minneapolis to Charleston, SC

    Looking for lower fares on your trip from Minneapolis to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Minneapolis to Charleston, SC