American Airlines flights from Minneapolis to Charleston, SC

Recent searches for flights from Minneapolis to Charleston, SC

Sep 2026
From$519*
Updated: 12 hours ago
Round tripIEconomy
Oct 2026
From$369*
Updated: 12 hours ago
Round tripIEconomy
Nov 2026
From$299*
Updated: 12 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $419
cmp-daily-histogram-bars-legend-max-price-aria-label $739
Displaying fares for September-2026
  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    15

    Tu

    SEP

  • MSP–CHS, 09/16/26 – 09/23/26: From $657
    16

    We

  • MSP–CHS, 09/17/26 – 09/24/26: From $657
    17

    Th

  • MSP–CHS, 09/18/26 – 09/25/26: From $657
    18

    Fr

  • MSP–CHS, 09/19/26 – 09/26/26: From $657
    19

    Sa

  • MSP–CHS, 09/20/26 – 09/27/26: From $657
    20

    Su

  • MSP–CHS, 09/21/26 – 09/28/26: From $657
    21

    Mo

  • MSP–CHS, 09/22/26 – 09/29/26: From $657
    22

    Tu

  • MSP–CHS, 09/23/26 – 09/30/26: From $657
    23

    We

  • MSP–CHS, 09/24/26 – 10/01/26: From $657
    24

    Th

  • MSP–CHS, 09/25/26 – 10/02/26: From $657
    25

    Fr

  • MSP–CHS, 09/26/26 – 10/03/26: From $657
    26

    Sa

  • MSP–CHS, 09/27/26 – 10/04/26: From $717
    27

    Su

  • MSP–CHS, 09/28/26 – 10/05/26: From $650
    28

    Mo

  • MSP–CHS, 09/29/26 – 10/06/26: From $519
    29

    Tu

  • MSP–CHS, 09/30/26 – 10/07/26: From $519
    30

    We

  • MSP–CHS, 10/01/26 – 10/08/26: From $684
    01

    Th

    OCT

  • MSP–CHS, 10/02/26 – 10/09/26: From $519
    02

    Fr

  • MSP–CHS, 10/03/26 – 10/10/26: From $519
    03

    Sa

  • MSP–CHS, 10/04/26 – 10/11/26: From $519
    04

    Su

  • MSP–CHS, 10/05/26 – 10/12/26: From $498
    05

    Mo

  • MSP–CHS, 10/06/26 – 10/13/26: From $429
    06

    Tu

  • MSP–CHS, 10/07/26 – 10/14/26: From $429
    07

    We

  • MSP–CHS, 10/08/26 – 10/15/26: From $494
    08

    Th

  • MSP–CHS, 10/09/26 – 10/16/26: From $419
    09

    Fr

  • MSP–CHS, 10/10/26 – 10/17/26: From $419
    10

    Sa

  • MSP–CHS, 10/11/26 – 10/18/26: From $739
    11

    Su

  • MSP–CHS, 10/12/26 – 10/19/26: From $586
    12

    Mo

  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

  • MSP–CHS: cmp-view-offers-disclaimer. Find Offers
    14

    We

    • range$419-$739

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Minneapolis to Charleston, SC flights

    $
    keyboard_arrow_down

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $334Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $334Fare subject to changes
    Updated: 12 hours ago

    Minneapolis (MSP)to

    Charleston, SC (CHS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 12 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Minneapolis to Charleston, SC

    Looking for lower fares on your trip from Minneapolis to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
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    American Airlines flights from Minneapolis to Charleston, SC