American Airlines flights from Indianapolis to Charleston, SC

Recent searches for flights from Indianapolis to Charleston, SC

Aug 2026
From$285*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$307*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$324*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $285
cmp-daily-histogram-bars-legend-max-price-aria-label $651
Displaying fares for August-2026
  • IND–CHS: cmp-view-offers-disclaimer. Find Offers
    04

    Tu

    AUG

  • IND–CHS, 08/05/26 – 08/12/26: From $525
    05

    We

  • IND–CHS, 08/06/26 – 08/13/26: From $651
    06

    Th

  • IND–CHS, 08/07/26 – 08/14/26: From $651
    07

    Fr

  • IND–CHS, 08/08/26 – 08/15/26: From $525
    08

    Sa

  • IND–CHS, 08/09/26 – 08/16/26: From $651
    09

    Su

  • IND–CHS, 08/10/26 – 08/17/26: From $651
    10

    Mo

  • IND–CHS, 08/11/26 – 08/18/26: From $491
    11

    Tu

  • IND–CHS, 08/12/26 – 08/19/26: From $491
    12

    We

  • IND–CHS, 08/13/26 – 08/20/26: From $582
    13

    Th

  • IND–CHS, 08/14/26 – 08/21/26: From $582
    14

    Fr

  • IND–CHS, 08/15/26 – 08/22/26: From $491
    15

    Sa

  • IND–CHS, 08/16/26 – 08/23/26: From $582
    16

    Su

  • IND–CHS, 08/17/26 – 08/24/26: From $574
    17

    Mo

  • IND–CHS, 08/18/26 – 08/25/26: From $285
    18

    Tu

  • IND–CHS, 08/19/26 – 08/26/26: From $285
    19

    We

  • IND–CHS, 08/20/26 – 08/27/26: From $373
    20

    Th

  • IND–CHS, 08/21/26 – 08/28/26: From $390
    21

    Fr

  • IND–CHS, 08/22/26 – 08/29/26: From $285
    22

    Sa

  • IND–CHS, 08/23/26 – 08/30/26: From $417
    23

    Su

  • IND–CHS, 08/24/26 – 08/31/26: From $373
    24

    Mo

  • IND–CHS, 08/25/26 – 09/01/26: From $285
    25

    Tu

  • IND–CHS, 08/26/26 – 09/02/26: From $285
    26

    We

  • IND–CHS, 08/27/26 – 09/03/26: From $329
    27

    Th

  • IND–CHS, 08/28/26 – 09/04/26: From $363
    28

    Fr

  • IND–CHS, 08/29/26 – 09/05/26: From $285
    29

    Sa

  • IND–CHS, 08/30/26 – 09/06/26: From $351
    30

    Su

  • IND–CHS, 08/31/26 – 09/07/26: From $422
    31

    Mo

  • IND–CHS: cmp-view-offers-disclaimer. Find Offers
    01

    Tu

    SEP

  • IND–CHS: cmp-view-offers-disclaimer. Find Offers
    02

    We

  • IND–CHS: cmp-view-offers-disclaimer. Find Offers
    03

    Th

    • range$285-$651

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Indianapolis to Charleston, SC flights

    $
    keyboard_arrow_down

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/19/26 - 08/26/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/18/26 - 08/25/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/22/26 - 08/29/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/25/26 - 09/01/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/26/26 - 09/02/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $285Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $307Fare subject to changes
    Updated: 1 hour ago

    Indianapolis (IND)to

    Charleston, SC (CHS)
    08/29/26 - 09/03/26

    Round trip

    Economy

    from
    $307Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Indianapolis to Charleston, SC

    Looking for lower fares on your trip from Indianapolis to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Indianapolis to Charleston, SC