American Airlines flights from Portland, OR to Charleston, SC

Recent searches for flights from Portland, OR to Charleston, SC

Sep 2026
From$518*
Updated: 6 hours ago
Round tripIEconomy
Oct 2026
From$235*
Updated: 6 hours ago
Round tripIEconomy
Nov 2026
From$235*
Updated: 6 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $365
cmp-daily-histogram-bars-legend-max-price-aria-label $955
Displaying fares for September-2026
  • PDX–CHS, 09/15/26 – 09/22/26: From $541
    15

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    SEP

  • PDX–CHS, 09/16/26 – 09/23/26: From $541
    16

    We

  • PDX–CHS, 09/17/26 – 09/24/26: From $626
    17

    Th

  • PDX–CHS, 09/18/26 – 09/25/26: From $626
    18

    Fr

  • PDX–CHS, 09/19/26 – 09/26/26: From $541
    19

    Sa

  • PDX–CHS, 09/20/26 – 09/27/26: From $787
    20

    Su

  • PDX–CHS, 09/21/26 – 09/28/26: From $592
    21

    Mo

  • PDX–CHS, 09/22/26 – 09/29/26: From $541
    22

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  • PDX–CHS, 09/23/26 – 09/30/26: From $537
    23

    We

  • PDX–CHS, 09/24/26 – 10/01/26: From $545
    24

    Th

  • PDX–CHS, 09/25/26 – 10/02/26: From $545
    25

    Fr

  • PDX–CHS, 09/26/26 – 10/03/26: From $541
    26

    Sa

  • PDX–CHS, 09/27/26 – 10/04/26: From $920
    27

    Su

  • PDX–CHS, 09/28/26 – 10/05/26: From $545
    28

    Mo

  • PDX–CHS, 09/29/26 – 10/06/26: From $518
    29

    Tu

  • PDX–CHS, 09/30/26 – 10/07/26: From $518
    30

    We

  • PDX–CHS, 10/01/26 – 10/08/26: From $592
    01

    Th

    OCT

  • PDX–CHS, 10/02/26 – 10/09/26: From $545
    02

    Fr

  • PDX–CHS, 10/03/26 – 10/10/26: From $518
    03

    Sa

  • PDX–CHS, 10/04/26 – 10/11/26: From $765
    04

    Su

  • PDX–CHS, 10/05/26 – 10/12/26: From $523
    05

    Mo

  • PDX–CHS, 10/06/26 – 10/13/26: From $518
    06

    Tu

  • PDX–CHS, 10/07/26 – 10/14/26: From $388
    07

    We

  • PDX–CHS, 10/08/26 – 10/15/26: From $523
    08

    Th

  • PDX–CHS, 10/09/26 – 10/16/26: From $421
    09

    Fr

  • PDX–CHS, 10/10/26 – 10/17/26: From $365
    10

    Sa

  • PDX–CHS, 10/11/26 – 10/18/26: From $955
    11

    Su

  • PDX–CHS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • PDX–CHS: cmp-view-offers-disclaimer. Find Offers
    13

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  • PDX–CHS: cmp-view-offers-disclaimer. Find Offers
    14

    We

    • range$365-$955

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, OR to Charleston, SC flights

    $
    keyboard_arrow_down

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    11/24/26 - 12/01/26

    Round trip

    Economy

    from
    $235Fare subject to changes
    Updated: 6 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, OR to Charleston, SC

    Looking for lower fares on your trip from Portland, OR to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Portland, OR to Charleston, SC