American Airlines flights from Portland, OR to Charleston, SC

Recent searches for flights from Portland, OR to Charleston, SC

Aug 2026
From$398*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$359*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$359*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $398
cmp-daily-histogram-bars-legend-max-price-aria-label $917
Displaying fares for August-2026
  • PDX–CHS, 08/04/26 – 08/11/26: From $521
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  • PDX–CHS, 08/05/26 – 08/12/26: From $521
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  • PDX–CHS, 08/06/26 – 08/13/26: From $687
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  • PDX–CHS, 08/07/26 – 08/15/26: From $604
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  • PDX–CHS, 08/08/26 – 08/15/26: From $623
    08

    Sa

  • PDX–CHS, 08/09/26 – 08/16/26: From $917
    09

    Su

  • PDX–CHS, 08/10/26 – 08/17/26: From $552
    10

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  • PDX–CHS, 08/11/26 – 08/18/26: From $481
    11

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  • PDX–CHS, 08/12/26 – 08/19/26: From $481
    12

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  • PDX–CHS, 08/13/26 – 08/20/26: From $525
    13

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  • PDX–CHS, 08/14/26 – 08/21/26: From $606
    14

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  • PDX–CHS, 08/15/26 – 08/22/26: From $550
    15

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  • PDX–CHS, 08/16/26 – 08/23/26: From $552
    16

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  • PDX–CHS, 08/17/26 – 08/24/26: From $491
    17

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  • PDX–CHS, 08/18/26 – 08/25/26: From $437
    18

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  • PDX–CHS, 08/19/26 – 08/26/26: From $437
    19

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  • PDX–CHS, 08/20/26 – 08/27/26: From $491
    20

    Th

  • PDX–CHS, 08/21/26 – 08/28/26: From $525
    21

    Fr

  • PDX–CHS, 08/22/26 – 08/29/26: From $437
    22

    Sa

  • PDX–CHS, 08/23/26 – 08/30/26: From $525
    23

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  • PDX–CHS, 08/24/26 – 08/31/26: From $457
    24

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  • PDX–CHS, 08/25/26 – 09/01/26: From $437
    25

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  • PDX–CHS, 08/26/26 – 09/02/26: From $398
    26

    We

  • PDX–CHS, 08/27/26 – 09/03/26: From $457
    27

    Th

  • PDX–CHS, 08/28/26 – 09/04/26: From $500
    28

    Fr

  • PDX–CHS, 08/29/26 – 09/05/26: From $398
    29

    Sa

  • PDX–CHS, 08/30/26 – 09/06/26: From $442
    30

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  • PDX–CHS, 08/31/26 – 09/07/26: From $640
    31

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  • PDX–CHS: cmp-view-offers-disclaimer. Find Offers
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    • range$398-$917

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, OR to Charleston, SC flights

    $
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    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    Portland, OR (PDX)to

    Charleston, SC (CHS)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, OR to Charleston, SC

    Looking for lower fares on your trip from Portland, OR to Charleston, SC? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Portland, OR to Charleston, SC