American Airlines flights from Myrtle Beach to San Diego

Recent searches for flights from Myrtle Beach to San Diego

Sep 2026
From$483*
Updated: 15 hours ago
Round tripIEconomy
Oct 2026
From$369*
Updated: 15 hours ago
Round tripIEconomy
Nov 2026
From$369*
Updated: 15 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $387
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • MYR–SAN, 09/11/26 – 09/18/26: From $1,062
    11

    Fr

    SEP

  • MYR–SAN, 09/12/26 – 09/19/26: From $1,060
    12

    Sa

  • MYR–SAN, 09/13/26 – 09/14/26: From $1,021
    13

    Su

  • MYR–SAN, 09/14/26 – 09/21/26: From $1,062
    14

    Mo

  • MYR–SAN, 09/15/26 – 09/22/26: From $1,017
    15

    Tu

  • MYR–SAN, 09/16/26 – 09/23/26: From $1,037
    16

    We

  • MYR–SAN, 09/17/26 – 09/24/26: From $908
    17

    Th

  • MYR–SAN, 09/18/26 – 09/25/26: From $847
    18

    Fr

  • MYR–SAN, 09/19/26 – 09/26/26: From $847
    19

    Sa

  • MYR–SAN, 09/20/26 – 09/27/26: From $847
    20

    Su

  • MYR–SAN, 09/21/26 – 09/28/26: From $847
    21

    Mo

  • MYR–SAN, 09/22/26 – 09/29/26: From $847
    22

    Tu

  • MYR–SAN, 09/23/26 – 09/30/26: From $847
    23

    We

  • MYR–SAN, 09/24/26 – 10/01/26: From $785
    24

    Th

  • MYR–SAN, 09/25/26 – 10/02/26: From $501
    25

    Fr

  • MYR–SAN, 09/26/26 – 10/03/26: From $544
    26

    Sa

  • MYR–SAN, 09/27/26 – 10/04/26: From $700
    27

    Su

  • MYR–SAN, 09/28/26 – 10/05/26: From $544
    28

    Mo

  • MYR–SAN, 09/29/26 – 10/06/26: From $483
    29

    Tu

  • MYR–SAN, 09/30/26 – 10/07/26: From $483
    30

    We

  • MYR–SAN, 10/01/26 – 10/08/26: From $658
    01

    Th

    OCT

  • MYR–SAN, 10/02/26 – 10/09/26: From $460
    02

    Fr

  • MYR–SAN, 10/03/26 – 10/10/26: From $442
    03

    Sa

  • MYR–SAN, 10/04/26 – 10/11/26: From $724
    04

    Su

  • MYR–SAN, 10/05/26 – 10/12/26: From $562
    05

    Mo

  • MYR–SAN, 10/06/26 – 10/13/26: From $483
    06

    Tu

  • MYR–SAN, 10/07/26 – 10/14/26: From $387
    07

    We

  • MYR–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Th

  • MYR–SAN, 10/09/26 – 10/12/26: From $474
    09

    Fr

  • MYR–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

    • range$387-$1,062

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to San Diego flights

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    Myrtle Beach (MYR)to

    San Diego (SAN)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    Myrtle Beach (MYR)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 15 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to San Diego

    Looking for lower fares on your trip from Myrtle Beach to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Myrtle Beach to San Diego