American Airlines flights from Rochester to Knoxville

Recent searches for flights from Rochester to Knoxville

Sep 2026
From$323*
Updated: 19 hours ago
Round tripIEconomy
Oct 2026
From$301*
Updated: 4 hours ago
Round tripIEconomy
Nov 2026
From$287*
Updated: 21 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $323
cmp-daily-histogram-bars-legend-max-price-aria-label $836
Displaying fares for September-2026
  • ROC–TYS, 09/04/26 – 09/11/26: From $686
    04

    Fr

    SEP

  • ROC–TYS, 09/05/26 – 09/12/26: From $483
    05

    Sa

  • ROC–TYS, 09/06/26 – 09/13/26: From $605
    06

    Su

  • ROC–TYS, 09/07/26 – 09/14/26: From $605
    07

    Mo

  • ROC–TYS, 09/08/26 – 09/15/26: From $483
    08

    Tu

  • ROC–TYS, 09/09/26 – 09/16/26: From $483
    09

    We

  • ROC–TYS, 09/10/26 – 09/17/26: From $605
    10

    Th

  • ROC–TYS, 09/11/26 – 09/18/26: From $566
    11

    Fr

  • ROC–TYS, 09/12/26 – 09/19/26: From $421
    12

    Sa

  • ROC–TYS, 09/13/26 – 09/20/26: From $642
    13

    Su

  • ROC–TYS, 09/14/26 – 09/21/26: From $605
    14

    Mo

  • ROC–TYS, 09/15/26 – 09/22/26: From $421
    15

    Tu

  • ROC–TYS, 09/16/26 – 09/23/26: From $421
    16

    We

  • ROC–TYS, 09/17/26 – 09/24/26: From $576
    17

    Th

  • ROC–TYS, 09/18/26 – 09/25/26: From $593
    18

    Fr

  • ROC–TYS, 09/19/26 – 09/26/26: From $323
    19

    Sa

  • ROC–TYS, 09/20/26 – 09/27/26: From $836
    20

    Su

  • ROC–TYS, 09/21/26 – 09/28/26: From $467
    21

    Mo

  • ROC–TYS, 09/22/26 – 09/29/26: From $354
    22

    Tu

  • ROC–TYS, 09/23/26 – 09/30/26: From $354
    23

    We

  • ROC–TYS, 09/24/26 – 10/01/26: From $605
    24

    Th

  • ROC–TYS, 09/25/26 – 10/02/26: From $723
    25

    Fr

  • ROC–TYS, 09/26/26 – 10/03/26: From $416
    26

    Sa

  • ROC–TYS, 09/27/26 – 10/04/26: From $627
    27

    Su

  • ROC–TYS, 09/28/26 – 10/05/26: From $414
    28

    Mo

  • ROC–TYS, 09/29/26 – 10/06/26: From $325
    29

    Tu

  • ROC–TYS, 09/30/26 – 10/07/26: From $325
    30

    We

  • ROC–TYS, 10/01/26 – 10/08/26: From $378
    01

    Th

    OCT

  • ROC–TYS: cmp-view-offers-disclaimer. Find Offers
    02

    Fr

  • ROC–TYS: cmp-view-offers-disclaimer. Find Offers
    03

    Sa

    • range$323-$836

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Rochester to Knoxville flights

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    keyboard_arrow_down

    Rochester (ROC)to

    Knoxville (TYS)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    Rochester (ROC)to

    Knoxville (TYS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Rochester to Knoxville

    Looking for lower fares on your trip from Rochester to Knoxville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
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    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Rochester to Knoxville