American Airlines flights from Seattle to Des Moines

Recent searches for flights from Seattle to Des Moines

Sep 2026
From$508*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$383*
Updated: 7 hours ago
Round tripIEconomy
Nov 2026
From$383*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $417
cmp-daily-histogram-bars-legend-max-price-aria-label $717
Displaying fares for September-2026
  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • SEA–DSM, 09/15/26 – 09/22/26: From $565
    15

    Tu

  • SEA–DSM, 09/16/26 – 09/23/26: From $565
    16

    We

  • SEA–DSM, 09/17/26 – 09/24/26: From $717
    17

    Th

  • SEA–DSM, 09/18/26 – 09/25/26: From $717
    18

    Fr

  • SEA–DSM, 09/19/26 – 09/26/26: From $565
    19

    Sa

  • SEA–DSM, 09/20/26 – 09/27/26: From $717
    20

    Su

  • SEA–DSM, 09/21/26 – 09/28/26: From $698
    21

    Mo

  • SEA–DSM, 09/22/26 – 09/29/26: From $565
    22

    Tu

  • SEA–DSM, 09/23/26 – 09/30/26: From $565
    23

    We

  • SEA–DSM, 09/24/26 – 10/01/26: From $698
    24

    Th

  • SEA–DSM, 09/25/26 – 10/02/26: From $698
    25

    Fr

  • SEA–DSM, 09/26/26 – 10/03/26: From $565
    26

    Sa

  • SEA–DSM, 09/27/26 – 10/04/26: From $698
    27

    Su

  • SEA–DSM, 09/28/26 – 10/05/26: From $524
    28

    Mo

  • SEA–DSM, 09/29/26 – 10/06/26: From $508
    29

    Tu

  • SEA–DSM, 09/30/26 – 10/07/26: From $508
    30

    We

  • SEA–DSM, 10/01/26 – 10/08/26: From $524
    01

    Th

    OCT

  • SEA–DSM, 10/02/26 – 10/09/26: From $524
    02

    Fr

  • SEA–DSM, 10/03/26 – 10/10/26: From $508
    03

    Sa

  • SEA–DSM, 10/04/26 – 10/11/26: From $547
    04

    Su

  • SEA–DSM, 10/05/26 – 10/12/26: From $474
    05

    Mo

  • SEA–DSM, 10/06/26 – 10/13/26: From $451
    06

    Tu

  • SEA–DSM, 10/07/26 – 10/14/26: From $417
    07

    We

  • SEA–DSM, 10/08/26 – 10/15/26: From $451
    08

    Th

  • SEA–DSM, 10/09/26 – 10/16/26: From $451
    09

    Fr

  • SEA–DSM, 10/10/26 – 10/17/26: From $417
    10

    Sa

  • SEA–DSM, 10/11/26 – 10/18/26: From $477
    11

    Su

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$417-$717

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Seattle to Des Moines flights

    $
    keyboard_arrow_down

    Seattle (SEA)to

    Des Moines (DSM)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    11/25/26 - 12/02/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    Seattle (SEA)to

    Des Moines (DSM)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Seattle to Des Moines

    Looking for lower fares on your trip from Seattle to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Seattle to Des Moines