American Airlines flights from Los Angeles to Des Moines

Recent searches for flights from Los Angeles to Des Moines

Aug 2026
From$375*
Updated: 13 hours ago
Round tripIEconomy
Sep 2026
From$157*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$226*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $157
cmp-daily-histogram-bars-legend-max-price-aria-label $463
Displaying fares for August-2026
  • LAX–DSM, 08/25/26 – 09/01/26: From $375
    25

    Tu

    AUG

  • LAX–DSM, 08/26/26 – 09/02/26: From $375
    26

    We

  • LAX–DSM, 08/27/26 – 09/02/26: From $414
    27

    Th

  • LAX–DSM, 08/28/26 – 09/04/26: From $453
    28

    Fr

  • LAX–DSM, 08/29/26 – 09/05/26: From $375
    29

    Sa

  • LAX–DSM, 08/30/26 – 09/06/26: From $453
    30

    Su

  • LAX–DSM, 08/31/26 – 09/07/26: From $463
    31

    Mo

  • LAX–DSM, 09/01/26 – 09/08/26: From $375
    01

    Tu

    SEP

  • LAX–DSM, 09/02/26 – 09/09/26: From $375
    02

    We

  • LAX–DSM, 09/03/26 – 09/10/26: From $463
    03

    Th

  • LAX–DSM, 09/04/26 – 09/07/26: From $427
    04

    Fr

  • LAX–DSM, 09/05/26 – 09/12/26: From $335
    05

    Sa

  • LAX–DSM, 09/06/26 – 09/13/26: From $384
    06

    Su

  • LAX–DSM, 09/07/26 – 09/14/26: From $434
    07

    Mo

  • LAX–DSM, 09/08/26 – 09/15/26: From $276
    08

    Tu

  • LAX–DSM, 09/09/26 – 09/16/26: From $226
    09

    We

  • LAX–DSM, 09/10/26 – 09/12/26: From $305
    10

    Th

  • LAX–DSM, 09/11/26 – 09/18/26: From $330
    11

    Fr

  • LAX–DSM, 09/12/26 – 09/19/26: From $226
    12

    Sa

  • LAX–DSM, 09/13/26 – 09/20/26: From $453
    13

    Su

  • LAX–DSM, 09/14/26 – 09/21/26: From $345
    14

    Mo

  • LAX–DSM, 09/15/26 – 09/22/26: From $157
    15

    Tu

  • LAX–DSM, 09/16/26 – 09/23/26: From $157
    16

    We

  • LAX–DSM, 09/17/26 – 09/24/26: From $368
    17

    Th

  • LAX–DSM, 09/18/26 – 09/25/26: From $365
    18

    Fr

  • LAX–DSM, 09/19/26 – 09/26/26: From $157
    19

    Sa

  • LAX–DSM, 09/20/26 – 09/27/26: From $430
    20

    Su

  • LAX–DSM, 09/21/26 – 09/28/26: From $345
    21

    Mo

  • LAX–DSM: cmp-view-offers-disclaimer. Find Offers
    22

    Tu

  • LAX–DSM, 09/23/26 – 09/27/26: From $341
    23

    We

  • LAX–DSM, 09/24/26 – 10/01/26: From $345
    24

    Th

    • range$157-$463

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Los Angeles to Des Moines flights

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    Los Angeles (LAX)to

    Des Moines (DSM)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    09/19/26 - 09/26/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    09/15/26 - 09/30/26

    Round trip

    Economy

    from
    $157Fare subject to changes
    Updated: 1 hour ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $226Fare subject to changes
    Updated: 3 hours ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $226Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Los Angeles to Des Moines

    Looking for lower fares on your trip from Los Angeles to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Los Angeles to Des Moines