American Airlines flights from Los Angeles to Des Moines

Recent searches for flights from Los Angeles to Des Moines

Sep 2026
From$415*
Updated: 31 minutes ago
Round tripIEconomy
Oct 2026
From$335*
Updated: 31 minutes ago
Round tripIEconomy
Nov 2026
From$335*
Updated: 31 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $375
cmp-daily-histogram-bars-legend-max-price-aria-label $503
Displaying fares for September-2026
  • LAX–DSM: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • LAX–DSM, 09/15/26 – 09/22/26: From $415
    15

    Tu

  • LAX–DSM, 09/16/26 – 09/23/26: From $415
    16

    We

  • LAX–DSM, 09/17/26 – 09/24/26: From $493
    17

    Th

  • LAX–DSM, 09/18/26 – 09/25/26: From $493
    18

    Fr

  • LAX–DSM, 09/19/26 – 09/26/26: From $415
    19

    Sa

  • LAX–DSM, 09/20/26 – 09/27/26: From $493
    20

    Su

  • LAX–DSM, 09/21/26 – 09/28/26: From $493
    21

    Mo

  • LAX–DSM, 09/22/26 – 09/29/26: From $415
    22

    Tu

  • LAX–DSM, 09/23/26 – 09/30/26: From $415
    23

    We

  • LAX–DSM, 09/24/26 – 10/01/26: From $493
    24

    Th

  • LAX–DSM, 09/25/26 – 10/02/26: From $503
    25

    Fr

  • LAX–DSM, 09/26/26 – 10/03/26: From $415
    26

    Sa

  • LAX–DSM, 09/27/26 – 10/04/26: From $503
    27

    Su

  • LAX–DSM, 09/28/26 – 10/05/26: From $503
    28

    Mo

  • LAX–DSM, 09/29/26 – 10/06/26: From $415
    29

    Tu

  • LAX–DSM, 09/30/26 – 10/07/26: From $415
    30

    We

  • LAX–DSM, 10/01/26 – 10/08/26: From $503
    01

    Th

    OCT

  • LAX–DSM, 10/02/26 – 10/09/26: From $493
    02

    Fr

  • LAX–DSM, 10/03/26 – 10/10/26: From $415
    03

    Sa

  • LAX–DSM, 10/04/26 – 10/11/26: From $503
    04

    Su

  • LAX–DSM, 10/05/26 – 10/07/26: From $485
    05

    Mo

  • LAX–DSM, 10/06/26 – 10/13/26: From $415
    06

    Tu

  • LAX–DSM, 10/07/26 – 10/14/26: From $375
    07

    We

  • LAX–DSM, 10/08/26 – 10/15/26: From $460
    08

    Th

  • LAX–DSM, 10/09/26 – 10/16/26: From $450
    09

    Fr

  • LAX–DSM, 10/10/26 – 10/17/26: From $375
    10

    Sa

  • LAX–DSM, 10/11/26 – 10/18/26: From $490
    11

    Su

  • LAX–DSM: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • LAX–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$375-$503

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Los Angeles to Des Moines flights

    $
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    Los Angeles (LAX)to

    Des Moines (DSM)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    Los Angeles (LAX)to

    Des Moines (DSM)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $335Fare subject to changes
    Updated: 31 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Los Angeles to Des Moines

    Looking for lower fares on your trip from Los Angeles to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Los Angeles to Des Moines