American Airlines flights from San Jose to Des Moines

Recent searches for flights from San Jose to Des Moines

Aug 2026
From$883*
Updated: 13 hours ago
Round tripIEconomy
Sep 2026
From$369*
Updated: 13 hours ago
Round tripIEconomy
Oct 2026
From$369*
Updated: 13 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $369
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • SJC–DSM, 08/25/26 – 09/01/26: From $1,015
    25

    Tu

    AUG

  • SJC–DSM, 08/26/26 – 09/02/26: From $1,015
    26

    We

  • SJC–DSM, 08/27/26 – 09/03/26: From $1,062
    27

    Th

  • SJC–DSM, 08/28/26 – 09/04/26: From $1,062
    28

    Fr

  • SJC–DSM, 08/29/26 – 09/05/26: From $1,033
    29

    Sa

  • SJC–DSM, 08/30/26 – 09/06/26: From $1,062
    30

    Su

  • SJC–DSM, 08/31/26 – 09/07/26: From $883
    31

    Mo

  • SJC–DSM, 09/01/26 – 09/08/26: From $842
    01

    Tu

    SEP

  • SJC–DSM, 09/02/26 – 09/09/26: From $842
    02

    We

  • SJC–DSM, 09/03/26 – 09/10/26: From $842
    03

    Th

  • SJC–DSM, 09/04/26 – 09/11/26: From $842
    04

    Fr

  • SJC–DSM, 09/05/26 – 09/12/26: From $483
    05

    Sa

  • SJC–DSM, 09/06/26 – 09/13/26: From $534
    06

    Su

  • SJC–DSM, 09/07/26 – 09/14/26: From $778
    07

    Mo

  • SJC–DSM, 09/08/26 – 09/15/26: From $483
    08

    Tu

  • SJC–DSM, 09/09/26 – 09/16/26: From $401
    09

    We

  • SJC–DSM, 09/10/26 – 09/17/26: From $401
    10

    Th

  • SJC–DSM, 09/11/26 – 09/18/26: From $379
    11

    Fr

  • SJC–DSM, 09/12/26 – 09/19/26: From $369
    12

    Sa

  • SJC–DSM, 09/13/26 – 09/20/26: From $572
    13

    Su

  • SJC–DSM, 09/14/26 – 09/21/26: From $433
    14

    Mo

  • SJC–DSM, 09/15/26 – 09/22/26: From $369
    15

    Tu

  • SJC–DSM, 09/16/26 – 09/23/26: From $369
    16

    We

  • SJC–DSM, 09/17/26 – 09/24/26: From $564
    17

    Th

  • SJC–DSM, 09/18/26 – 09/25/26: From $515
    18

    Fr

  • SJC–DSM, 09/19/26 – 09/26/26: From $369
    19

    Sa

  • SJC–DSM, 09/20/26 – 09/27/26: From $566
    20

    Su

  • SJC–DSM, 09/21/26 – 09/28/26: From $455
    21

    Mo

  • SJC–DSM: cmp-view-offers-disclaimer. Find Offers
    22

    Tu

  • SJC–DSM: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • SJC–DSM, 09/24/26 – 09/28/26: From $420
    24

    Th

    • range$369-$1,062

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Jose to Des Moines flights

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    San Jose (SJC)to

    Des Moines (DSM)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    San Jose (SJC)to

    Des Moines (DSM)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 13 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Jose to Des Moines

    Looking for lower fares on your trip from San Jose to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from San Jose to Des Moines