American Airlines flights from Sioux Falls to Panama City

Recent searches for flights from Sioux Falls to Panama City

Aug 2026
From$401*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$301*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$306*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $320
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • FSD–ECP, 08/23/26 – 08/30/26: From $655
    23

    Su

    AUG

  • FSD–ECP, 08/24/26 – 08/31/26: From $524
    24

    Mo

  • FSD–ECP, 08/25/26 – 09/01/26: From $406
    25

    Tu

  • FSD–ECP, 08/26/26 – 09/02/26: From $401
    26

    We

  • FSD–ECP, 08/27/26 – 09/03/26: From $529
    27

    Th

  • FSD–ECP, 08/28/26 – 09/04/26: From $484
    28

    Fr

  • FSD–ECP, 08/29/26 – 09/05/26: From $401
    29

    Sa

  • FSD–ECP, 08/30/26 – 09/06/26: From $538
    30

    Su

  • FSD–ECP, 08/31/26 – 09/07/26: From $1,132
    31

    Mo

  • FSD–ECP, 09/01/26 – 09/08/26: From $595
    01

    Tu

    SEP

  • FSD–ECP, 09/02/26 – 09/09/26: From $438
    02

    We

  • FSD–ECP, 09/03/26 – 09/10/26: From $901
    03

    Th

  • FSD–ECP, 09/04/26 – 09/11/26: From $765
    04

    Fr

  • FSD–ECP, 09/05/26 – 09/15/26: From $389
    05

    Sa

  • FSD–ECP, 09/06/26 – 09/13/26: From $595
    06

    Su

  • FSD–ECP, 09/07/26 – 09/14/26: From $611
    07

    Mo

  • FSD–ECP, 09/08/26 – 09/15/26: From $384
    08

    Tu

  • FSD–ECP, 09/09/26 – 09/16/26: From $436
    09

    We

  • FSD–ECP, 09/10/26 – 09/17/26: From $539
    10

    Th

  • FSD–ECP, 09/11/26 – 09/15/26: From $498
    11

    Fr

  • FSD–ECP, 09/12/26 – 09/19/26: From $529
    12

    Sa

  • FSD–ECP, 09/13/26 – 09/20/26: From $797
    13

    Su

  • FSD–ECP, 09/14/26 – 09/21/26: From $557
    14

    Mo

  • FSD–ECP, 09/15/26 – 09/22/26: From $320
    15

    Tu

  • FSD–ECP, 09/16/26 – 09/23/26: From $545
    16

    We

  • FSD–ECP, 09/17/26 – 09/24/26: From $609
    17

    Th

  • FSD–ECP, 09/18/26 – 09/25/26: From $653
    18

    Fr

  • FSD–ECP, 09/19/26 – 09/26/26: From $447
    19

    Sa

  • FSD–ECP: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • FSD–ECP: cmp-view-offers-disclaimer. Find Offers
    21

    Mo

  • FSD–ECP, 09/22/26 – 09/29/26: From $320
    22

    Tu

    • range$320-$1,132

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Sioux Falls to Panama City flights

    $
    keyboard_arrow_down

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $301Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $306Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $306Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $311Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $311Fare subject to changes
    Updated: 1 hour ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $315Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Sioux Falls to Panama City

    Looking for lower fares on your trip from Sioux Falls to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Sioux Falls to Panama City