American Airlines flights from Sioux Falls to Panama City

Recent searches for flights from Sioux Falls to Panama City

Sep 2026
From$374*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$321*
Updated: 2 hours ago
Round tripIEconomy
Nov 2026
From$326*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $374
cmp-daily-histogram-bars-legend-max-price-aria-label $1.0K
Displaying fares for September-2026
  • FSD–ECP, 09/12/26 – 09/19/26: From $529
    12

    Sa

    SEP

  • FSD–ECP, 09/13/26 – 09/20/26: From $1,000
    13

    Su

  • FSD–ECP, 09/14/26 – 09/21/26: From $728
    14

    Mo

  • FSD–ECP, 09/15/26 – 09/22/26: From $426
    15

    Tu

  • FSD–ECP, 09/16/26 – 09/23/26: From $465
    16

    We

  • FSD–ECP, 09/17/26 – 09/24/26: From $778
    17

    Th

  • FSD–ECP, 09/18/26 – 09/25/26: From $583
    18

    Fr

  • FSD–ECP, 09/19/26 – 09/26/26: From $410
    19

    Sa

  • FSD–ECP, 09/20/26 – 09/27/26: From $907
    20

    Su

  • FSD–ECP, 09/21/26 – 09/28/26: From $670
    21

    Mo

  • FSD–ECP, 09/22/26 – 09/29/26: From $415
    22

    Tu

  • FSD–ECP, 09/23/26 – 09/30/26: From $571
    23

    We

  • FSD–ECP, 09/24/26 – 10/01/26: From $654
    24

    Th

  • FSD–ECP, 09/25/26 – 10/02/26: From $718
    25

    Fr

  • FSD–ECP, 09/26/26 – 10/03/26: From $374
    26

    Sa

  • FSD–ECP, 09/27/26 – 10/04/26: From $817
    27

    Su

  • FSD–ECP, 09/28/26 – 10/05/26: From $745
    28

    Mo

  • FSD–ECP, 09/29/26 – 10/06/26: From $379
    29

    Tu

  • FSD–ECP, 09/30/26 – 10/07/26: From $481
    30

    We

  • FSD–ECP, 10/01/26 – 10/08/26: From $790
    01

    Th

    OCT

  • FSD–ECP, 10/02/26 – 10/09/26: From $631
    02

    Fr

  • FSD–ECP, 10/03/26 – 10/10/26: From $451
    03

    Sa

  • FSD–ECP, 10/04/26 – 10/11/26: From $1,008
    04

    Su

  • FSD–ECP, 10/05/26 – 10/12/26: From $785
    05

    Mo

  • FSD–ECP, 10/06/26 – 10/13/26: From $579
    06

    Tu

  • FSD–ECP, 10/07/26 – 10/14/26: From $554
    07

    We

  • FSD–ECP, 10/08/26 – 10/15/26: From $779
    08

    Th

  • FSD–ECP, 10/09/26 – 10/16/26: From $753
    09

    Fr

  • FSD–ECP: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

  • FSD–ECP: cmp-view-offers-disclaimer. Find Offers
    11

    Su

    • range$374-$1,008

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Sioux Falls to Panama City flights

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    Sioux Falls (FSD)to

    Panama City (ECP)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $326Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $326Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $326Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $326Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    Panama City (ECP)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $326Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Sioux Falls to Panama City

    Looking for lower fares on your trip from Sioux Falls to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
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    American Airlines flights from Sioux Falls to Panama City