American Airlines flights from Destin
expand_more
1 Adult, Economy class
expand_moreexpand_more
today
today
Popular flights from Destin
flight_takeoff
flight_land
$
Destin (VPS)to
Dallas (DFW)03/05/26 - 03/07/26from$419Fare subject to changesUpdated: 11 hours agoRound tripEconomy
Destin (VPS)to
Washington, D.C. (DCA)03/05/26 - 03/08/26from$466Fare subject to changesUpdated: 4 hours agoRound tripEconomy
Destin (VPS)to
Miami (MIA)03/17/26 - 03/21/26from$330Fare subject to changesUpdated: 10 hours agoRound tripEconomy
Destin (VPS)to
Charlotte (CLT)03/21/26 - 03/29/26from$356Fare subject to changesUpdated: 14 hours agoRound tripEconomy
Destin (VPS)to
Las Vegas (LAS)03/16/26 - 03/18/26from$565Fare subject to changesUpdated: 9 hours agoRound tripEconomy
Destin (VPS)to
Boston (BOS)03/11/26 - 03/14/26from$355Fare subject to changesUpdated: 1 hour agoRound tripEconomy
Destin (VPS)to
Phoenix (PHX)03/16/26 - 03/19/26from$565Fare subject to changesUpdated: 8 hours agoRound tripEconomy
Destin (VPS)to
Seattle (SEA)03/17/26 - 03/23/26from$521Fare subject to changesUpdated: 9 hours agoRound tripEconomy
Destin (VPS)to
Chicago (ORD)03/07/26 - 03/12/26from$397Fare subject to changesUpdated: 10 hours agoRound tripEconomy
Destin (VPS)to
Oklahoma City (OKC)03/09/26 - 03/10/26from$563Fare subject to changesUpdated: 9 hours agoRound tripEconomy
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
Find deals on flights from Destin
flight_takeoff
flight_land
$
Destin (VPS)to
Dallas (DFW)
04/10/26 - 04/12/26
Round trip
Economy
from
$351Fare subject to changes
Updated: 5 hours ago
Destin (VPS)to
Washington, D.C. (DCA)
07/01/26 - 07/15/26
Round trip
Economy
from
$302Fare subject to changes
Updated: 8 hours ago
Destin (VPS)to
Miami (MIA)
04/04/26 - 04/11/26
Round trip
Economy
from
$242Fare subject to changes
Updated: 2 hours ago
Destin (VPS)to
Charlotte (CLT)
06/09/26 - 06/15/26
Round trip
Economy
from
$325Fare subject to changes
Updated: 14 hours ago
Destin (VPS)to
Las Vegas (LAS)
05/12/26 - 05/15/26
Round trip
Economy
from
$427Fare subject to changes
Updated: 7 hours ago
Destin (VPS)to
Phoenix (PHX)
04/22/26 - 04/29/26
Round trip
Economy
from
$348Fare subject to changes
Updated: 10 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
With an expansive network of destinations, your world is a flight away
To search for a great fare, start by selecting your departure city. Looking to book using miles? Try our miles finder map.