American Airlines flights from Destin to San Diego

Recent searches for flights from Destin to San Diego

Jul 2026
From$695*
Updated: 2 hours ago
Round tripIEconomy
Aug 2026
From$367*
Updated: 2 hours ago
Round tripIEconomy
Sep 2026
From$367*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $367
cmp-daily-histogram-bars-legend-max-price-aria-label $876
Displaying fares for July-2026
  • VPS–SAN: cmp-view-offers-disclaimer. Find Offers
    29

    We

    JUL

  • VPS–SAN, 07/30/26 – 08/06/26: From $695
    30

    Th

  • VPS–SAN, 07/31/26 – 08/07/26: From $695
    31

    Fr

  • VPS–SAN, 08/01/26 – 08/08/26: From $533
    01

    Sa

    AUG

  • VPS–SAN, 08/02/26 – 08/09/26: From $695
    02

    Su

  • VPS–SAN, 08/03/26 – 08/10/26: From $695
    03

    Mo

  • VPS–SAN, 08/04/26 – 08/11/26: From $533
    04

    Tu

  • VPS–SAN, 08/05/26 – 08/12/26: From $533
    05

    We

  • VPS–SAN, 08/06/26 – 08/13/26: From $645
    06

    Th

  • VPS–SAN, 08/07/26 – 08/14/26: From $651
    07

    Fr

  • VPS–SAN, 08/08/26 – 08/15/26: From $876
    08

    Sa

  • VPS–SAN, 08/09/26 – 08/22/26: From $537
    09

    Su

  • VPS–SAN, 08/10/26 – 08/17/26: From $645
    10

    Mo

  • VPS–SAN, 08/11/26 – 08/18/26: From $533
    11

    Tu

  • VPS–SAN, 08/12/26 – 08/19/26: From $450
    12

    We

  • VPS–SAN, 08/13/26 – 08/20/26: From $481
    13

    Th

  • VPS–SAN, 08/14/26 – 08/21/26: From $522
    14

    Fr

  • VPS–SAN, 08/15/26 – 08/22/26: From $450
    15

    Sa

  • VPS–SAN, 08/16/26 – 08/23/26: From $571
    16

    Su

  • VPS–SAN, 08/17/26 – 08/24/26: From $481
    17

    Mo

  • VPS–SAN, 08/18/26 – 08/25/26: From $417
    18

    Tu

  • VPS–SAN, 08/19/26 – 08/26/26: From $367
    19

    We

  • VPS–SAN, 08/20/26 – 08/27/26: From $367
    20

    Th

  • VPS–SAN, 08/21/26 – 08/28/26: From $449
    21

    Fr

  • VPS–SAN, 08/22/26 – 08/29/26: From $367
    22

    Sa

  • VPS–SAN, 08/23/26 – 08/30/26: From $503
    23

    Su

  • VPS–SAN, 08/24/26 – 08/31/26: From $367
    24

    Mo

  • VPS–SAN, 08/25/26 – 09/01/26: From $367
    25

    Tu

  • VPS–SAN: cmp-view-offers-disclaimer. Find Offers
    26

    We

  • VPS–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Th

  • VPS–SAN: cmp-view-offers-disclaimer. Find Offers
    28

    Fr

    • range$367-$876

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Destin to San Diego flights

    $
    keyboard_arrow_down

    Destin (VPS)to

    San Diego (SAN)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    09/24/26 - 10/01/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    08/19/26 - 08/26/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    Destin (VPS)to

    San Diego (SAN)
    08/22/26 - 08/29/26

    Round trip

    Economy

    from
    $367Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Destin to San Diego

    Looking for lower fares on your trip from Destin to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $400 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Destin to San Diego