
American Airlines flights to Knoxville from $159*
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1 Adult, Economy class
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today
today
Popular flights to Knoxville on American Airlines
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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Knoxville
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Dallas (DFW)to
Knoxville (TYS)
07/10/25 - 07/11/25
Round trip
I
Economy
from
$259Fare subject to changes
Updated: 8 hours ago
Philadelphia (PHL)to
Knoxville (TYS)
07/05/25 - 07/09/25
Round trip
I
Economy
from
$351Fare subject to changes
Updated: 43 minutes ago
Chicago (ORD)to
Knoxville (TYS)
07/25/25 - 08/01/25
Round trip
I
Economy
from
$189Fare subject to changes
Updated: 4 hours ago
Washington, D.C. (DCA)to
Knoxville (TYS)
07/04/25 - 07/11/25
Round trip
I
Economy
from
$184Fare subject to changes
Updated: 3 hours ago
Phoenix (PHX)to
Knoxville (TYS)
07/01/25 - 07/08/25
Round trip
I
Economy
from
$259Fare subject to changes
Updated: 3 hours ago
New York (LGA)to
Knoxville (TYS)
07/22/25 - 07/29/25
Round trip
I
Economy
from
$179Fare subject to changes
Updated: 2 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
Knoxville routes with American Airlines
- Dallas - Knoxville
- Philadelphia - Knoxville
- Chicago - Knoxville
- Phoenix - Knoxville
- New York - Knoxville
- Austin - Knoxville
- Omaha - Knoxville
- Orlando - Knoxville
- Ontario - Knoxville
- Miami - Knoxville
- Los Angeles - Knoxville
- San Francisco - Knoxville
- Orange County - Knoxville
- San Diego - Knoxville
- Baltimore - Knoxville