American Airlines flights to Panama City from $141*

Popular flights to Panama City on American Airlines

$
keyboard_arrow_down

  • Phoenix (PHX)to

    Panama City (ECP)
    06/24/25 - 07/01/25
    from
    $291Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Los Angeles (LAX)to

    Panama City (ECP)
    06/25/25 - 07/02/25
    from
    $325Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Austin (AUS)to

    Panama City (ECP)
    08/01/25 - 08/08/25
    from
    $217Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Denver (DEN)to

    Panama City (ECP)
    07/01/25 - 07/08/25
    from
    $347Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

  • Chicago (ORD)to

    Panama City (ECP)
    06/07/25 - 06/14/25
    from
    $227Fare subject to changes
    Updated: 7 hours ago
    Round trip
    I
    Economy

    Fayetteville (XNA)to

    Panama City (ECP)
    07/04/25 - 07/11/25
    from
    $224Fare subject to changes
    Updated: 35 minutes ago
    Round trip
    I
    Economy

    Cincinnati (CVG)to

    Panama City (ECP)
    07/27/25 - 08/03/25
    from
    $257Fare subject to changes
    Updated: 18 hours ago
    Round trip
    I
    Economy

    Indianapolis (IND)to

    Panama City (ECP)
    08/06/25 - 08/13/25
    from
    $157Fare subject to changes
    Updated: 13 hours ago
    Round trip
    I
    Economy

  • Harrisburg (MDT)to

    Panama City (ECP)
    07/04/25 - 07/11/25
    from
    $224Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Miami (MIA)to

    Panama City (ECP)
    06/24/25 - 07/01/25
    from
    $267Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Pittsburgh (PIT)to

    Panama City (ECP)
    07/01/25 - 07/08/25
    from
    $287Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Saint Louis (STL)to

    Panama City (ECP)
    08/13/25 - 08/20/25
    from
    $167Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

  • Boston (BOS)to

    Panama City (ECP)
    05/31/25 - 06/07/25
    from
    $310Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Tulsa (TUL)to

    Panama City (ECP)
    08/15/25 - 08/22/25
    from
    $257Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Columbus (CMH)to

    Panama City (ECP)
    06/24/25 - 07/01/25
    from
    $257Fare subject to changes
    Updated: 8 minutes ago
    Round trip
    I
    Economy

    Nashville (BNA)to

    Panama City (ECP)
    08/11/25 - 08/18/25
    from
    $167Fare subject to changes
    Updated: 43 minutes ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Panama City from **Flights.FromLowestPrice***

Find deals on flights to Panama City

$
keyboard_arrow_down

Dallas (DFW)to

Panama City (ECP)
07/05/25 - 07/12/25

Round trip

I

Economy

from
$141Fare subject to changes
Updated: 22 hours ago

Charlotte (CLT)to

Panama City (ECP)
07/22/25 - 07/29/25

Round trip

I

Economy

from
$313Fare subject to changes
Updated: 2 hours ago

Philadelphia (PHL)to

Panama City (ECP)
06/25/25 - 07/02/25

Round trip

I

Economy

from
$328Fare subject to changes
Updated: 1 hour ago

Washington, D.C. (DCA)to

Panama City (ECP)
06/24/25 - 07/01/25

Round trip

I

Economy

from
$303Fare subject to changes
Updated: 1 hour ago

Phoenix (PHX)to

Panama City (ECP)
07/01/25 - 07/08/25

Round trip

I

Economy

from
$291Fare subject to changes
Updated: 4 hours ago

Los Angeles (LAX)to

Panama City (ECP)
06/24/25 - 07/01/25

Round trip

I

Economy

from
$325Fare subject to changes
Updated: 4 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Panama City routes with American Airlines