American Airlines flights to Santiago from $464*

Popular flights to Santiago on American Airlines

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  • Boston (BOS)to

    Santiago (SCL)
    08/14/25 - 08/21/25
    from
    $664Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Charlotte (CLT)to

    Santiago (SCL)
    07/22/25 - 07/29/25
    from
    $804Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Chicago (ORD)to

    Santiago (SCL)
    07/16/25 - 07/23/25
    from
    $874Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Philadelphia (PHL)to

    Santiago (SCL)
    07/22/25 - 07/29/25
    from
    $804Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

  • Seattle (SEA)to

    Santiago (SCL)
    08/19/25 - 08/26/25
    from
    $1,108Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Washington, D.C. (DCA)to

    Santiago (SCL)
    08/05/25 - 08/12/25
    from
    $814Fare subject to changes
    Updated: 10 hours ago
    Round trip
    I
    Economy

    New York (NYC)to

    Santiago (SCL)
    06/02/25 - 06/09/25
    from
    $614Fare subject to changes
    Updated: 9 hours ago
    Round trip
    I
    Economy

    New York (JFK)to

    Santiago (SCL)
    05/29/25 - 06/05/25
    from
    $614Fare subject to changes
    Updated: 10 hours ago
    Round trip
    I
    Economy

  • Denver (DEN)to

    Santiago (SCL)
    08/12/25 - 08/19/25
    from
    $634Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

    Washington, D.C. (WAS)to

    Santiago (SCL)
    07/27/25 - 08/03/25
    from
    $794Fare subject to changes
    Updated: 7 hours ago
    Round trip
    I
    Economy

    Austin (AUS)to

    Santiago (SCL)
    08/06/25 - 08/13/25
    from
    $684Fare subject to changes
    Updated: 12 hours ago
    Round trip
    I
    Economy

    Orlando (MCO)to

    Santiago (SCL)
    05/29/25 - 06/05/25
    from
    $464Fare subject to changes
    Updated: 47 minutes ago
    Round trip
    I
    Economy

  • Houston (IAH)to

    Santiago (SCL)
    08/04/25 - 08/11/25
    from
    $1,364Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    New York/Newark (EWR)to

    Santiago (SCL)
    05/29/25 - 06/05/25
    from
    $614Fare subject to changes
    Updated: 3 hours ago
    Round trip
    I
    Economy

    Kansas City (MCI)to

    Santiago (SCL)
    07/16/25 - 07/23/25
    from
    $878Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Phoenix (PHX)to

    Santiago (SCL)
    08/18/25 - 08/25/25
    from
    $904Fare subject to changes
    Updated: 1 hour ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santiago from **Flights.FromLowestPrice***

Find deals on flights to Santiago

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Miami (MIA)to

Santiago (SCL)
09/17/25 - 09/24/25

Round trip

I

Economy

from
$594Fare subject to changes
Updated: 1 hour ago

Dallas (DFW)to

Santiago (SCL)
01/13/26 - 01/22/26

Round trip

I

Economy

from
$639Fare subject to changes
Updated: 4 hours ago

Los Angeles (LAX)to

Santiago (SCL)
08/28/25 - 09/04/25

Round trip

I

Economy

from
$774Fare subject to changes
Updated: 1 hour ago

San Francisco (SFO)to

Santiago (SCL)
08/14/25 - 08/21/25

Round trip

I

Economy

from
$664Fare subject to changes
Updated: 9 hours ago

Boston (BOS)to

Santiago (SCL)
01/27/26 - 02/15/26

Round trip

I

Economy

from
$518Fare subject to changes
Updated: 13 hours ago

Charlotte (CLT)to

Santiago (SCL)
09/17/25 - 09/24/25

Round trip

I

Economy

from
$754Fare subject to changes
Updated: 1 hour ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Santiago routes with American Airlines