American Airlines flights to Santiago from $464*

Popular flights to Santiago on American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santiago from **Flights.FromLowestPrice***

Find deals on flights to Santiago

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Miami (MIA)to

Santiago (SCL)
10/28/25 - 11/04/25

Round trip

Economy

from
$563Fare subject to changes
Updated: 15 hours ago

Dallas (DFW)to

Santiago (SCL)
03/04/26 - 03/11/26

Round trip

Economy

from
$639Fare subject to changes
Updated: 13 hours ago

Denver (DEN)to

Santiago (SCL)
11/25/25 - 12/06/25

Round trip

Economy

from
$608Fare subject to changes
Updated: 8 hours ago

San Francisco (SFO)to

Santiago (SCL)
08/31/25 - 09/13/25

Round trip

Economy

from
$672Fare subject to changes
Updated: 15 hours ago

Los Angeles (LAX)to

Santiago (SCL)
10/30/25 - 11/06/25

Round trip

Economy

from
$774Fare subject to changes
Updated: 6 hours ago

Philadelphia (PHL)to

Santiago (SCL)
10/30/25 - 11/06/25

Round trip

Economy

from
$804Fare subject to changes
Updated: 9 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Santiago routes with American Airlines