American Airlines flights from Greensboro to Des Moines

Recent searches for flights from Greensboro to Des Moines

Sep 2026
From$354*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$339*
Updated: 5 hours ago
Round tripIEconomy
Nov 2026
From$339*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $339
cmp-daily-histogram-bars-legend-max-price-aria-label $625
Displaying fares for September-2026
  • GSO–DSM: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • GSO–DSM, 09/15/26 – 09/22/26: From $441
    15

    Tu

  • GSO–DSM, 09/16/26 – 09/23/26: From $441
    16

    We

  • GSO–DSM, 09/17/26 – 09/24/26: From $444
    17

    Th

  • GSO–DSM, 09/18/26 – 09/25/26: From $444
    18

    Fr

  • GSO–DSM, 09/19/26 – 09/26/26: From $441
    19

    Sa

  • GSO–DSM, 09/20/26 – 09/27/26: From $616
    20

    Su

  • GSO–DSM, 09/21/26 – 09/28/26: From $399
    21

    Mo

  • GSO–DSM, 09/22/26 – 09/29/26: From $399
    22

    Tu

  • GSO–DSM, 09/23/26 – 09/30/26: From $399
    23

    We

  • GSO–DSM, 09/24/26 – 10/01/26: From $567
    24

    Th

  • GSO–DSM, 09/25/26 – 10/02/26: From $399
    25

    Fr

  • GSO–DSM, 09/26/26 – 10/03/26: From $399
    26

    Sa

  • GSO–DSM, 09/27/26 – 10/04/26: From $601
    27

    Su

  • GSO–DSM, 09/28/26 – 10/05/26: From $354
    28

    Mo

  • GSO–DSM, 09/29/26 – 10/06/26: From $354
    29

    Tu

  • GSO–DSM, 09/30/26 – 10/07/26: From $354
    30

    We

  • GSO–DSM, 10/01/26 – 10/08/26: From $433
    01

    Th

    OCT

  • GSO–DSM, 10/02/26 – 10/09/26: From $537
    02

    Fr

  • GSO–DSM, 10/03/26 – 10/10/26: From $354
    03

    Sa

  • GSO–DSM, 10/04/26 – 10/11/26: From $433
    04

    Su

  • GSO–DSM, 10/05/26 – 10/12/26: From $339
    05

    Mo

  • GSO–DSM, 10/06/26 – 10/13/26: From $339
    06

    Tu

  • GSO–DSM, 10/07/26 – 10/14/26: From $339
    07

    We

  • GSO–DSM, 10/08/26 – 10/15/26: From $522
    08

    Th

  • GSO–DSM, 10/09/26 – 10/16/26: From $513
    09

    Fr

  • GSO–DSM, 10/10/26 – 10/17/26: From $396
    10

    Sa

  • GSO–DSM, 10/11/26 – 10/18/26: From $625
    11

    Su

  • GSO–DSM: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • GSO–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$339-$625

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Greensboro to Des Moines flights

    $
    keyboard_arrow_down

    Greensboro (GSO)to

    Des Moines (DSM)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    12/04/26 - 12/11/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    12/07/26 - 12/14/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    11/15/26 - 11/22/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    Greensboro (GSO)to

    Des Moines (DSM)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $339Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Greensboro to Des Moines

    Looking for lower fares on your trip from Greensboro to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
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    American Airlines flights from Greensboro to Des Moines