American Airlines flights from Mcallen to San Diego

Recent searches for flights from Mcallen to San Diego

Aug 2026
From$845*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$321*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$321*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $321
cmp-daily-histogram-bars-legend-max-price-aria-label $845
Displaying fares for August-2026
  • MFE–SAN, 08/31/26 – 09/07/26: From $845
    31

    Mo

    AUG

  • MFE–SAN, 09/01/26 – 09/08/26: From $424
    01

    Tu

  • MFE–SAN, 09/02/26 – 09/09/26: From $401
    02

    We

  • MFE–SAN, 09/03/26 – 09/10/26: From $503
    03

    Th

  • MFE–SAN, 09/04/26 – 09/11/26: From $531
    04

    Fr

  • MFE–SAN, 09/05/26 – 09/12/26: From $401
    05

    Sa

  • MFE–SAN, 09/06/26 – 09/13/26: From $390
    06

    Su

  • MFE–SAN, 09/07/26 – 09/14/26: From $845
    07

    Mo

  • MFE–SAN, 09/08/26 – 09/15/26: From $515
    08

    Tu

  • MFE–SAN, 09/09/26 – 09/16/26: From $401
    09

    We

  • MFE–SAN, 09/10/26 – 09/17/26: From $365
    10

    Th

  • MFE–SAN, 09/11/26 – 09/18/26: From $468
    11

    Fr

  • MFE–SAN, 09/12/26 – 09/19/26: From $361
    12

    Sa

  • MFE–SAN, 09/13/26 – 09/20/26: From $460
    13

    Su

  • MFE–SAN, 09/14/26 – 09/21/26: From $493
    14

    Mo

  • MFE–SAN, 09/15/26 – 09/22/26: From $370
    15

    Tu

  • MFE–SAN, 09/16/26 – 09/23/26: From $370
    16

    We

  • MFE–SAN, 09/17/26 – 09/24/26: From $374
    17

    Th

  • MFE–SAN, 09/18/26 – 09/25/26: From $374
    18

    Fr

  • MFE–SAN, 09/19/26 – 09/26/26: From $370
    19

    Sa

  • MFE–SAN, 09/20/26 – 09/27/26: From $433
    20

    Su

  • MFE–SAN, 09/21/26 – 09/28/26: From $399
    21

    Mo

  • MFE–SAN, 09/22/26 – 09/29/26: From $330
    22

    Tu

  • MFE–SAN, 09/23/26 – 09/30/26: From $330
    23

    We

  • MFE–SAN, 09/24/26 – 10/01/26: From $399
    24

    Th

  • MFE–SAN, 09/25/26 – 10/02/26: From $399
    25

    Fr

  • MFE–SAN, 09/26/26 – 10/03/26: From $330
    26

    Sa

  • MFE–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Su

  • MFE–SAN: cmp-view-offers-disclaimer. Find Offers
    28

    Mo

  • MFE–SAN: cmp-view-offers-disclaimer. Find Offers
    29

    Tu

  • MFE–SAN, 09/30/26 – 10/07/26: From $321
    30

    We

    • range$321-$845

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Mcallen to San Diego flights

    $
    keyboard_arrow_down

    Mcallen (MFE)to

    San Diego (SAN)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    Mcallen (MFE)to

    San Diego (SAN)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Mcallen to San Diego

    Looking for lower fares on your trip from Mcallen to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Mcallen to San Diego