American Airlines flights from Sioux Falls to San Diego

Recent searches for flights from Sioux Falls to San Diego

Aug 2026
From$433*
Updated: 2 hours ago
Round tripIEconomy
Sep 2026
From$321*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$321*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $330
cmp-daily-histogram-bars-legend-max-price-aria-label $719
Displaying fares for August-2026
  • FSD–SAN, 08/26/26 – 09/02/26: From $433
    26

    We

    AUG

  • FSD–SAN, 08/27/26 – 09/03/26: From $509
    27

    Th

  • FSD–SAN, 08/28/26 – 09/04/26: From $509
    28

    Fr

  • FSD–SAN, 08/29/26 – 09/05/26: From $433
    29

    Sa

  • FSD–SAN, 08/30/26 – 09/06/26: From $509
    30

    Su

  • FSD–SAN, 08/31/26 – 09/07/26: From $719
    31

    Mo

  • FSD–SAN, 09/01/26 – 09/08/26: From $433
    01

    Tu

    SEP

  • FSD–SAN, 09/02/26 – 09/09/26: From $421
    02

    We

  • FSD–SAN, 09/03/26 – 09/10/26: From $444
    03

    Th

  • FSD–SAN, 09/04/26 – 09/11/26: From $507
    04

    Fr

  • FSD–SAN, 09/05/26 – 09/12/26: From $365
    05

    Sa

  • FSD–SAN, 09/06/26 – 09/13/26: From $463
    06

    Su

  • FSD–SAN, 09/07/26 – 09/14/26: From $507
    07

    Mo

  • FSD–SAN, 09/08/26 – 09/15/26: From $421
    08

    Tu

  • FSD–SAN, 09/09/26 – 09/16/26: From $330
    09

    We

  • FSD–SAN, 09/10/26 – 09/17/26: From $330
    10

    Th

  • FSD–SAN, 09/11/26 – 09/18/26: From $330
    11

    Fr

  • FSD–SAN, 09/12/26 – 09/19/26: From $330
    12

    Sa

  • FSD–SAN, 09/13/26 – 09/20/26: From $665
    13

    Su

  • FSD–SAN, 09/14/26 – 09/21/26: From $551
    14

    Mo

  • FSD–SAN, 09/15/26 – 09/22/26: From $374
    15

    Tu

  • FSD–SAN, 09/16/26 – 09/23/26: From $339
    16

    We

  • FSD–SAN, 09/17/26 – 09/24/26: From $542
    17

    Th

  • FSD–SAN, 09/18/26 – 09/25/26: From $339
    18

    Fr

  • FSD–SAN, 09/19/26 – 09/26/26: From $330
    19

    Sa

  • FSD–SAN, 09/20/26 – 09/27/26: From $621
    20

    Su

  • FSD–SAN, 09/21/26 – 09/28/26: From $472
    21

    Mo

  • FSD–SAN, 09/22/26 – 09/29/26: From $330
    22

    Tu

  • FSD–SAN: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • FSD–SAN: cmp-view-offers-disclaimer. Find Offers
    24

    Th

  • FSD–SAN, 09/25/26 – 10/02/26: From $406
    25

    Fr

    • range$330-$719

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Sioux Falls to San Diego flights

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    Sioux Falls (FSD)to

    San Diego (SAN)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    Sioux Falls (FSD)to

    San Diego (SAN)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $321Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Sioux Falls to San Diego

    Looking for lower fares on your trip from Sioux Falls to San Diego? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Sioux Falls to San Diego