American Airlines flights from Milwaukee to Des Moines

Recent searches for flights from Milwaukee to Des Moines

Jul 2026
From$1,017*
Updated: 21 hours ago
Round tripIEconomy
Aug 2026
From$249*
Updated: 1 hour ago
Round tripIEconomy
Sep 2026
From$249*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $249
cmp-daily-histogram-bars-legend-max-price-aria-label $1.5K
Displaying fares for July-2026
  • MKE–DSM, 07/30/26 – 08/06/26: From $1,017
    30

    Th

    JUL

  • MKE–DSM, 07/31/26 – 08/07/26: From $1,017
    31

    Fr

  • MKE–DSM, 08/01/26 – 08/08/26: From $1,450
    01

    Sa

    AUG

  • MKE–DSM, 08/02/26 – 08/09/26: From $1,060
    02

    Su

  • MKE–DSM, 08/03/26 – 08/10/26: From $830
    03

    Mo

  • MKE–DSM, 08/04/26 – 08/11/26: From $609
    04

    Tu

  • MKE–DSM, 08/05/26 – 08/12/26: From $609
    05

    We

  • MKE–DSM, 08/06/26 – 08/13/26: From $634
    06

    Th

  • MKE–DSM, 08/07/26 – 08/14/26: From $527
    07

    Fr

  • MKE–DSM, 08/08/26 – 08/15/26: From $527
    08

    Sa

  • MKE–DSM, 08/09/26 – 08/16/26: From $588
    09

    Su

  • MKE–DSM, 08/10/26 – 08/17/26: From $634
    10

    Mo

  • MKE–DSM, 08/11/26 – 08/18/26: From $527
    11

    Tu

  • MKE–DSM, 08/12/26 – 08/19/26: From $527
    12

    We

  • MKE–DSM, 08/13/26 – 08/20/26: From $404
    13

    Th

  • MKE–DSM, 08/14/26 – 08/21/26: From $378
    14

    Fr

  • MKE–DSM, 08/15/26 – 08/22/26: From $353
    15

    Sa

  • MKE–DSM, 08/16/26 – 08/23/26: From $407
    16

    Su

  • MKE–DSM, 08/17/26 – 08/24/26: From $404
    17

    Mo

  • MKE–DSM, 08/18/26 – 08/25/26: From $353
    18

    Tu

  • MKE–DSM, 08/19/26 – 08/26/26: From $353
    19

    We

  • MKE–DSM, 08/20/26 – 08/27/26: From $249
    20

    Th

  • MKE–DSM, 08/21/26 – 08/28/26: From $299
    21

    Fr

  • MKE–DSM, 08/22/26 – 08/29/26: From $249
    22

    Sa

  • MKE–DSM, 08/23/26 – 08/30/26: From $337
    23

    Su

  • MKE–DSM, 08/24/26 – 08/31/26: From $249
    24

    Mo

  • MKE–DSM, 08/25/26 – 09/01/26: From $249
    25

    Tu

  • MKE–DSM, 08/26/26 – 09/02/26: From $249
    26

    We

  • MKE–DSM: cmp-view-offers-disclaimer. Find Offers
    27

    Th

  • MKE–DSM: cmp-view-offers-disclaimer. Find Offers
    28

    Fr

  • MKE–DSM, 08/29/26 – 09/05/26: From $249
    29

    Sa

    • range$249-$1,450

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Milwaukee to Des Moines flights

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    Milwaukee (MKE)to

    Des Moines (DSM)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    09/19/26 - 09/26/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    09/01/26 - 09/08/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    08/24/26 - 08/31/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    Milwaukee (MKE)to

    Des Moines (DSM)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $249Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Milwaukee to Des Moines

    Looking for lower fares on your trip from Milwaukee to Des Moines? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Milwaukee to Des Moines